Targeted drug delivery—from magic bullet to nanomedicine: principles, challenges, and future perspectives

A Tewabe, A Abate, M Tamrie, A Seyfu… - Journal of …, 2021 - Taylor & Francis
Nanomedicine is an advanced version of Paul Ehrlich's “magic bullet” concept. Targeted
drug delivery is a system of specifying the drug moiety directly into its targeted body area …

[HTML][HTML] Transfersomes: A promising nanoencapsulation technique for transdermal drug delivery

SAT Opatha, V Titapiwatanakun, R Chutoprapat - Pharmaceutics, 2020 - mdpi.com
Transdermal delivery systems have gained much interest in recent years owing to their
advantages compared to conventional oral and parenteral delivery systems. They are …

Hollow microneedles: A perspective in biomedical applications

Á Cárcamo-Martínez, B Mallon… - International journal of …, 2021 - Elsevier
Microneedles (MN) have the potential to become a highly progressive device for both drug
delivery and monitoring purposes as they penetrate the skin and pierce the stratum corneum …

Lipid nanocarriers as skin drug delivery systems: Properties, mechanisms of skin interactions and medical applications

M Sala, R Diab, A Elaissari, H Fessi - International journal of pharmaceutics, 2018 - Elsevier
During the past decades, lipid nanocarriers are gaining momentum with their multiple
advantages for the management of skin diseases. Lipid nanocarriers enable to target the …

Nanotechnology-empowered strategies in treatment of skin cancer

J Chandra, N Hasan, N Nasir, S Wahab… - Environmental …, 2023 - Elsevier
In current scenario skin cancer is a serious condition that has a significant impact on world
health. Skin cancer is divided into two categories: melanoma skin cancer (MSC) and non …

Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape

C Zylberberg, S Matosevic - Drug delivery, 2016 - Taylor & Francis
Liposomes were the first nanoscale drug to be approved for clinical use in 1995. Since then,
the technology has grown considerably, and pioneering recent work in liposome-based …

Challenges associated with penetration of nanoparticles across cell and tissue barriers: a review of current status and future prospects

S Barua, S Mitragotri - Nano today, 2014 - Elsevier
Nanoparticles (NPs) have emerged as an effective modality for the treatment of various
diseases including cancer, cardiovascular and inflammatory diseases. Various forms of NPs …

Ethosomal nanocarriers: the impact of constituents and formulation techniques on ethosomal properties, in vivo studies, and clinical trials

IM Abdulbaqi, Y Darwis, NAK Khan… - International journal …, 2016 - Taylor & Francis
Ethosomal systems are novel lipid vesicular carriers containing a relatively high percentage
of ethanol. These nanocarriers are especially designed for the efficient delivery of …

Lipid vesicles: A versatile drug delivery platform for dermal and transdermal applications

IA Chacko, VM Ghate, L Dsouza, SA Lewis - Colloids and Surfaces B …, 2020 - Elsevier
Topical and transdermal application of active pharmaceutical ingredients to the skin is an
attractive strategy being explored by formulation scientists to treat disease conditions rather …

Approaches for breaking the barriers of drug permeation through transdermal drug delivery

A Alexander, S Dwivedi, TK Giri, S Saraf, S Saraf… - Journal of controlled …, 2012 - Elsevier
Transdermal drug delivery system (TDDS) utilizes the skin as executable route for drug
administration but the foremost barrier against drug permeability is the stratum corneum and …