The Americas In 2007, Poser and Brinar 1 noted that published prevalence rates of multiple
sclerosis (MS) could be misleading with the reliance on clinical information and brain MRI …

Background: The incidence and prevalence of multiple sclerosis (MS) varies considerably
around the world. No previous study has performed a comprehensive review examining the …

Objectives Previous studies have demonstrated a strong latitudinal gradient in multiple
sclerosis (MS) prevalence. Herein, we present a meta-analysis of the latitudinal gradient of …

The strongest epidemiological clue that the environment at the population level has a
significant impact on the risk of developing multiple sclerosis is the well established, and in …

Multiple sclerosis (MS) is a chronic debilitating inflammatory disease of unknown ethology
targeting the central nervous system (CNS). MS has a polysymptomatic onset and is usually …

Previous studies revealed a latitudinal gradient of multiple sclerosis (MS) prevalence,
increasing by moving from the equator to the poles. The duration and quality of an …

Background Although the economic burden of multiple sclerosis (MS) in high-income
countries (HICs) has been extensively studied, information on the costs of MS in low-and …

Human skin pigmentation evolved as a compromise between the conflicting physiological
demands of protection against the deleterious effects of ultraviolet radiation (UVR) and …

Objective Previous studies assessing seasonal variation of relapse onset in multiple
sclerosis have had conflicting results. Small relapse numbers, differing diagnostic criteria …

OBJECTIVES: The epidemiology of eosinophilic esophagitis (EoE) is rapidly evolving, and
differences in climate could impact the prevalence of EoE. We aimed to examine the …