[HTML][HTML] Therapeutics of osteoarthritis and pharmacological mechanisms: A focus on RANK/RANKL signaling
J Liang, L Liu, H Feng, Y Yue, Y Zhang, Q Wang… - Biomedicine & …, 2023 - Elsevier
Osteoarthritis (OA) is a chronic degenerative disease afflicting millions globally. Despite the
development of numerous pharmacological treatments for OA, a substantial unmet need for …
development of numerous pharmacological treatments for OA, a substantial unmet need for …
Magnetic targeting of lornoxicam/SPION bilosomes loaded in a thermosensitive in situ hydrogel system for the management of osteoarthritis: Optimization, in vitro, ex …
Osteoarthritis is a bone and joint condition characterized pathologically by articular cartilage
degenerative damage and can develop into a devastating and permanently disabling …
degenerative damage and can develop into a devastating and permanently disabling …
Total glucosides of white paeony capsule alleviate articular cartilage degeneration and aberrant subchondral bone remodeling in knee osteoarthritis
T Liao, J Kang, Z Ma, L Jie, M Feng, D Liu… - Phytotherapy …, 2024 - Wiley Online Library
Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that is primarily
managed by improving the destroyed cartilage and reversing subchondral bone remodeling …
managed by improving the destroyed cartilage and reversing subchondral bone remodeling …
Chondroitin Sulphate-Chitosan polyelectrolyte complexes for etorocoxib transdermal delivery: in silico, in vitro and in vivo studies
Rheumatoid arthritis (RA) is a chronic autoimmune disease which affects around 1%
globally leading to joint inflammation and disability. Etorocoxib (ETR) is a potent COX-2 …
globally leading to joint inflammation and disability. Etorocoxib (ETR) is a potent COX-2 …
Insights into the Roles of Natural Killer Cells in Osteoarthritis
CQ Zheng, LJ Zeng, ZH Liu, CF Miao… - Immunological …, 2024 - Taylor & Francis
Osteoarthritis (OA) is now widely acknowledged as a low-grade inflammatory condition, in
which the intrinsic immune system plays a significant role in its pathogenesis. While the …
which the intrinsic immune system plays a significant role in its pathogenesis. While the …
[HTML][HTML] L-Arginine-induced acute pancreatitis and its associated lung injury in rats: Down-regulation of TLR-4/MAPK-p38/JNK signaling pathway via Ginkgo biloba …
RE Mostafa, SS Abdelrahmen… - Iranian Journal of Basic …, 2024 - ncbi.nlm.nih.gov
Objective (s): Acute pancreatitis (AP) is an abrupt inflammatory condition characterized by a
storm of inflammatory cytokines leading to high morbidity and mortality. The current study …
storm of inflammatory cytokines leading to high morbidity and mortality. The current study …
Meclizine moderates lipopolysaccharide-induced neuroinflammation in mice through the regulation of AKT/NF-κβ/ERK/JNK signaling pathway
RE Mostafa, GF Asaad - Metabolic Brain Disease, 2023 - Springer
Neuroinflammation is identified as significant inflammatory reactions occurring in the central
nervous system. Lipopolysaccharide (LPS) stimulates innate immune reactions and is used …
nervous system. Lipopolysaccharide (LPS) stimulates innate immune reactions and is used …
Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of phlorizin against osteoarthritis
Y Yao, Q Zhong, Y Zhong, Z Gao, B Zhou, C Lu… - Naunyn-Schmiedeberg's …, 2024 - Springer
To study the pharmacological effects and mechanisms of phlorizin in the treatment of
osteoarthritis (OA) through network pharmacological analysis, molecular docking, and …
osteoarthritis (OA) through network pharmacological analysis, molecular docking, and …