Background & Aims There is controversy regarding the overall value of hepatocellular
carcinoma (HCC) surveillance in patients with cirrhosis given the lack of data from …

The burden of hepatocellular carcinoma (HCC) is highest in East Asia and Africa, although
its incidence and mortality are rapidly rising in the United States and Europe. With the …

Hepatocellular cancer (HCC) is the fourth leading cause of cancer-related deaths worldwide
and the fastest growing cause of cancer deaths in the United States. The overall prognosis …

Predictive machine-learning systems often do not convey the degree of confidence in the
correctness of their outputs. To prevent unsafe prediction failures from machine-learning …

Importance Unrealistic patient expectations of the benefits and harms of interventions can
influence decision making and may be contributing to increasing intervention uptake and …

Abstract Background: According to the Wonca International Dictionary for General/Family
Practice Quaternary Prevention is defined as:'Action taken to identify patient at risk of …

Although surveillance ultrasound and alpha fetoprotein (AFP) tests have minimal direct
harm, downstream harms from follow‐up tests must be weighed against surveillance …

Background Ultrasound visualisation is limited in approximately 20% of patients with
cirrhosis undergoing hepatocellular carcinoma (HCC) surveillance; however, it is unknown if …

Why cancer screening has never been shown to “save lives”—and what we can do about it
Page 1 Why cancer screening has never been shown to “save lives”—and what we can do …

Overdiagnosis refers to detection of disease that would not otherwise become clinically
apparent during a patient's lifetime. Overdiagnosis is common and has been reported for …