Mechanisms of bacterial transcription termination: all good things must end
A Ray-Soni, MJ Bellecourt… - Annual review of …, 2016 - annualreviews.org
Transcript termination is essential for accurate gene expression and the removal of RNA
polymerase (RNAP) at the ends of transcription units. In bacteria, two mechanisms are …
polymerase (RNAP) at the ends of transcription units. In bacteria, two mechanisms are …
Coupling of RNA polymerase II transcription elongation with pre-mRNA splicing
T Saldi, MA Cortazar, RM Sheridan… - Journal of molecular …, 2016 - Elsevier
Pre-mRNA maturation frequently occurs at the same time and place as transcription by RNA
polymerase II. The co-transcriptionality of mRNA processing has permitted the evolution of …
polymerase II. The co-transcriptionality of mRNA processing has permitted the evolution of …
Native elongating transcript sequencing reveals human transcriptional activity at nucleotide resolution
Major features of transcription by human RNA polymerase II (Pol II) remain poorly defined
due to a lack of quantitative approaches for visualizing Pol II progress at nucleotide …
due to a lack of quantitative approaches for visualizing Pol II progress at nucleotide …
A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery
In prokaryotes, translation can occur on mRNA that is being transcribed in a process called
coupling. How the ribosome affects the RNA polymerase (RNAP) during coupling is not well …
coupling. How the ribosome affects the RNA polymerase (RNAP) during coupling is not well …
Mechanisms of bacterial transcription termination
JW Roberts - Journal of molecular biology, 2019 - Elsevier
Bacterial transcription termination, described mostly for Escherichia coli, occurs in three
recognized ways: intrinsic termination, an activity only of the core RNAP enzyme and …
recognized ways: intrinsic termination, an activity only of the core RNAP enzyme and …
The pausing zone and control of RNA polymerase II elongation by Spt5: Implications for the pause-release model
The pause-release model of transcription proposes that 40–100 bases from the start site
RNA Pol II pauses, followed by release into productive elongation. Pause release is …
RNA Pol II pauses, followed by release into productive elongation. Pause release is …
Transcription-translation coupling in bacteria
In bacteria, transcription and translation take place in the same cellular compartment.
Therefore, a messenger RNA can be translated as it is being transcribed, a process known …
Therefore, a messenger RNA can be translated as it is being transcribed, a process known …
Initial events in bacterial transcription initiation
EF Ruff, MT Record Jr, I Artsimovitch - Biomolecules, 2015 - mdpi.com
Transcription initiation is a highly regulated step of gene expression. Here, we discuss the
series of large conformational changes set in motion by initial specific binding of bacterial …
series of large conformational changes set in motion by initial specific binding of bacterial …
Structural basis for NusA stabilized transcriptional pausing
X Guo, AG Myasnikov, J Chen, C Crucifix, G Papai… - Molecular cell, 2018 - cell.com
Transcriptional pausing by RNA polymerases (RNAPs) is a key mechanism to regulate gene
expression in all kingdoms of life and is a prerequisite for transcription termination. The …
expression in all kingdoms of life and is a prerequisite for transcription termination. The …
RNA polymerase accommodates a pause RNA hairpin by global conformational rearrangements that prolong pausing
Sequence-specific pausing by RNA polymerase (RNAP) during transcription plays crucial
and diverse roles in gene expression. In bacteria, RNA structures are thought to fold within …
and diverse roles in gene expression. In bacteria, RNA structures are thought to fold within …