Primary and secondary endosymbiosis and the origin of plastids

GI McFadden - Journal of Phycology, 2001 - Wiley Online Library
The theory of endosymbiosis describes the origin of plastids from cyanobacterial‐like
prokaryotes living within eukaryotic host cells. The endosymbionts are much reduced, but …

The apicoplast: a plastid in Plasmodium falciparum and other Apicomplexan parasites

BJ Foth, GI McFadden - International review of cytology, 2003 - Elsevier
Apicomplexan parasites cause severe diseases such as malaria, toxoplasmosis, and
coccidiosis (caused by Plasmodium spp., Toxoplasma, and Eimeria, respectively). These …

Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

H Jomaa, J Wiesner, S Sanderbrand, B Altincicek… - Science, 1999 - science.org
A mevalonate-independent pathway of isoprenoid biosynthesis present in Plasmodium
falciparum was shown to represent an effective target for chemotherapy of malaria. This …

Transformation of the diatom Phaeodactylum tricornutum (Bacillariophyceae) with a variety of selectable marker and reporter genes

LA Zaslavskaia, JC Lippmeier, PG Kroth… - Journal of …, 2000 - Wiley Online Library
A general purpose transformation vector, designated pPha‐T1, was constructed for use with
the diatom Phaeodactylum tricornutum Bohlin. This vector harbors the sh ble cassette for …

[HTML][HTML] Protein trafficking to the plastid of Plasmodium falciparum is via the secretory pathway

RF Waller, MB Reed, AF Cowman… - The EMBO journal, 2000 - embopress.org
The plastid of Plasmodium falciparum (or 'apicoplast') is the evolutionary homolog of the
plant chloroplast and represents a vestige of a photosynthetic past. Apicoplast …

The Plastid of Toxoplasma gondii Is Divided by Association with the Centrosomes

B Striepen, MJ Crawford, MK Shaw, LG Tilney… - The Journal of cell …, 2000 - rupress.org
Apicomplexan parasites harbor a single nonphotosynthetic plastid, the apicoplast, which is
essential for parasite survival. Exploiting Toxoplasma gondii as an accessible system for cell …

Endosymbiosis and evolution of the plant cell

GI McFadden - Current opinion in plant biology, 1999 - Elsevier
The bacterial origins of plastid division and protein import by plastids are beginning to
emerge—thanks largely to the availability of a total genome sequence for a cyanobacterium …

Origin, targeting, and function of the apicomplexan plastid

DS Roos, MJ Crawford, RGK Donald… - Current opinion in …, 1999 - Elsevier
The discovery of a plastid in Plasmodium, Toxoplasma and related protozoan parasites
provides a satisfying resolution to several long-standing mysteries: the mechanism of action …

The apicomplexan plastid and its evolution

S Sato - Cellular and Molecular Life Sciences, 2011 - Springer
Protistan species belonging to the phylum Apicomplexa have a non-photosynthetic
secondary plastid—the apicoplast. Although its tiny genome and even the entire nuclear …

The signal sequence of exported protein-1 directs the green fluorescent protein to the parasitophorous vacuole of transfected malaria parasites

A Adisa, M Rug, N Klonis, M Foley, AF Cowman… - Journal of Biological …, 2003 - ASBMB
The malaria parasite, Plasmodium falciparum, spends part of its life cycle inside the
erythrocytes of its human host. In the mature stages of intraerythrocytic growth, the parasite …