Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of
biliary tract differentiation. CCA is the second most common primary liver tumour and the …

Primary liver cancer (PLC) is the fourth most frequent cause of cancer-related death. The
high mortality rates arise from late diagnosis and the limited accuracy of diagnostic and …

Cholangiocarcinoma (CCA) is an epithelial can-cer originating from the bile ducts with
features of cholangiocyte differentiation. 1 CCA is the second most common primary hepatic …

Cholangiocarcinoma (CCA) is a heterogeneous group of malignancies with features of
biliary tract differentiation. CCA is the second most common primary liver tumour and the …

Intrahepatic cholangiocarcinoma (ICC) is an aggressive malignancy with very poor
prognosis. Genome-wide, high-throughput technologies have made major advances in …

The intrahepatic bile ducts comprise a complex 3-di-mensional network of conduits within
the liver lined by specialized epithelial cells called cholangiocytes. A major function of …

Celecoxib is a paradigmatic selective inhibitor of cyclooxygenase-2 (COX-2). This anti-
inflammatory drug has potent anti-tumor activity in a wide variety of human epithelial tumor …

Cholangiocarcinomas are devastating cancers that are increasing in both their worldwide
incidence and mortality rates. The challenges posed by these often lethal biliary tract …

Biliary tract cancers (BTCs) are a group of invasive neoplasms, with increasing incidence
and dismal prognosis. In advanced disease, the standard of care is represented by first-line …

Cholangiocellular carcinoma (CC), the second most common primary liver cancer, is
associated with a poor prognosis. It has been shown that CCs harbor alterations of a …