Mid-trimester preterm premature rupture of membranes (PPROM), defined as rupture of fetal
membranes prior to 28 weeks of gestation, complicates approximately 0.4%–0.7% of all …

Importance Bronchopulmonary dysplasia (BPD) has multifactorial etiology and long-term
adverse consequences. An umbrella review enables the evaluation of multiple proposed …

Objective The purpose of this study was to compare intraamniotic inflammation vs microbial
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …

Citation DiGiulio DB, Romero R, Kusanovic JP, Gómez R, Kim CJ, Seok K, Gotsch F, Mazaki‐
Tovi S, Vaisbuch E, Sanders K, Bik EM, Chaiworapongsa T, Oyarzún E, Relman DA …

Background Intra-amniotic infection is present in 10% of patients with an episode of preterm
labor, and is a risk factor for impending preterm delivery and neonatal morbidity/mortality …

Preterm birth remains the most serious complication of pregnancy and is associated with
increased rates of infant death or permanent neurodevelopmental disability. Our …

The purpose of this study was to determine whether the administration of clindamycin to
women with abnormal vaginal flora at< 22 weeks of gestation reduces the risk of preterm …

Infection-related preterm birth (PTB) is more common at early gestational ages and is
associated with major neonatal mortality and morbidity. Abnormal genital tract microflora in …

Objectives: To determine whether a new antibiotic regimen could reduce the frequency of
intra-amniotic inflammation/infection in patients with preterm PROM. Study design: This …

Objective: Antibiotic administration is a standard practice in preterm premature rupture of
membranes (PROM). Specific anti-microbial agents often include ampicillin and/or …