Characterization of the SARS‐CoV‐2 E protein: sequence, structure, viroporin, and inhibitors

Y Cao, R Yang, I Lee, W Zhang, J Sun, W Wang… - Protein …, 2021 - Wiley Online Library
The COVID‐19 epidemic is one of the most influential epidemics in history. Understanding
the impact of coronaviruses (CoVs) on host cells is very important for disease treatment. The …

Lipid and lipid raft alteration in aging and neurodegenerative diseases: a window for the development of new biomarkers

F Mesa-Herrera, L Taoro-González… - International journal of …, 2019 - mdpi.com
Lipids in the brain are major components playing structural functions as well as
physiological roles in nerve cells, such as neural communication, neurogenesis, synaptic …

Modulation of inflammation in brain: a matter of fat

AA Farooqui, LA Horrocks… - Journal of …, 2007 - Wiley Online Library
Neuroinflammation is a host defense mechanism associated with neutralization of an insult
and restoration of normal structure and function of brain. Neuroinflammation is a hallmark of …

Lipid rafts, cholesterol, and the brain

Z Korade, AK Kenworthy - Neuropharmacology, 2008 - Elsevier
Lipid rafts are specialized membrane microdomains that serve as organizing centers for
assembly of signaling molecules, influence membrane fluidity and trafficking of membrane …

The gap junction cellular internet: connexin hemichannels enter the signalling limelight

WH Evans, E De Vuyst, L Leybaert - Biochemical Journal, 2006 - portlandpress.com
Cxs (connexins), the protein subunits forming gap junction intercellular communication
channels, are transported to the plasma membrane after oligomerizing into hexameric …

Rhamnolipids Are Virulence Factors That Promote Early Infiltration of Primary Human Airway Epithelia by Pseudomonas aeruginosa

L Zulianello, C Canard, T Köhler, D Caille… - Infection and …, 2006 - Am Soc Microbiol
The opportunistic bacterium Pseudomonas aeruginosa causes chronic respiratory infections
in cystic fibrosis and immunocompromised individuals. Bacterial adherence to the …

[HTML][HTML] Membrane proteins structures: A review on computational modeling tools

JG Almeida, AJ Preto, PI Koukos, AMJJ Bonvin… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Abstract Background Membrane proteins (MPs) play diverse and important functions in
living organisms. They constitute 20% to 30% of the known bacterial, archaean and …

Cholesterol reduction impairs exocytosis of synaptic vesicles

A Linetti, A Fratangeli, E Taverna… - Journal of Cell …, 2010 - journals.biologists.com
Cholesterol and sphingolipids are abundant in neuronal membranes, where they help the
organisation of the membrane microdomains involved in major roles such as axonal and …

Developing and testing of lipid force fields with applications to modeling cellular membranes

AN Leonard, E Wang, V Monje-Galvan… - Chemical …, 2019 - ACS Publications
The amphipathic nature of the lipid molecule (hydrophilic head and hydrophobic tails)
enables it to act as a barrier between fluids with various properties and to sustain an …

[HTML][HTML] Large neutral amino acid levels tune perinatal neuronal excitability and survival

LS Knaus, B Basilico, D Malzl, MG Bujalkova… - Cell, 2023 - cell.com
Little is known about the critical metabolic changes that neural cells have to undergo during
development and how temporary shifts in this program can influence brain circuitries and …