▪ Abstract The primary function of bacterial recombination systems is the nonmutagenic
repair of stalled or collapsed replication forks. The RecA protein plays a central role in these …

In bacteria, the major function of homologous genetic recombination is re-combinational
DNA repair. This is not a process reserved only for rare double-strand breaks caused by …

▪ Abstract It has recently become clear that the recombinational repair of stalled replication
forks is the primary function of homologous recombination systems in bacteria. In spite of the …

RecA protein filaments formed on circular (ssDNA) in the presence of ssDNA binding protein
(SSB) are generally stable as long as ATP is regenerated. On linear ssDNA, stable RecA …

One of the authors (AJC) acknowledges with gratitude the important role Fernando
Bastarrachea played in the author's discovery that E. coli could carry out homologous …

DNA double-strand-break repair (DSBR) is, in many organisms, accomplished by
homologous recombination. In Escherichia coli DSBR was thought to result from breakage …

Abstract The Escherichia coli RecF, RecO and RecR pro teins have previously been
implicated in bacterial recombinational DNA repair at DNA gaps. The RecOR‐facilitated …

RecA, the key protein in homologous recombination, performs its actions as a helical
filament on single-stranded DNA (ssDNA). ATP hydrolysis makes the RecA–ssDNA filament …

Aspects of the molecular mechanism of “adaptive” mutation are emerging from one
experimental system: reversion of an Escherichia coli lac frameshift mutation carried on a …

Major advances in understanding the molecular mechanism of recombination-dependent
stationary-phase mutation in Escherichia coli occurred this past year. These advances are …