New strategies and mechanisms for targeting Streptococcus mutans biofilm formation to prevent dental caries: a review

Z Gao, X Chen, C Wang, J Song, J Xu, X Liu… - Microbiological …, 2024 - Elsevier
Dental caries, a prevalent oral infectious disease, is intricately linked to the biofilm formation
on the tooth surfaces by oral microbes. Among these, Streptococcus mutans plays a central …

Quorum sensing and bacterial social interactions in biofilms

YH Li, X Tian - Sensors, 2012 - mdpi.com
Many bacteria are known to regulate their cooperative activities and physiological processes
through a mechanism called quorum sensing (QS), in which bacterial cells communicate …

Quorum Sensing Regulation of Competence and Bacteriocins in Streptococcus pneumoniae and mutans

E Shanker, MJ Federle - Genes, 2017 - mdpi.com
The human pathogens Streptococcus pneumoniae and Streptococcus mutans have both
evolved complex quorum sensing (QS) systems that regulate the production of bacteriocins …

A stress-inducible quorum-sensing peptide mediates the formation of persister cells with noninherited multidrug tolerance

V Leung, CM Lévesque - Journal of bacteriology, 2012 - Am Soc Microbiol
Within a given microbial population, a small subpopulation known as dormant persister cells
exists. This persistence property ensures the survival of the population as a whole in the …

Mucin O-glycans suppress quorum-sensing pathways and genetic transformation in Streptococcus mutans

CA Werlang, WG Chen, K Aoki, KM Wheeler… - Nature …, 2021 - nature.com
Mucus barriers accommodate trillions of microorganisms throughout the human body while
preventing pathogenic colonization. In the oral cavity, saliva containing the mucins MUC5B …

Regulation of competence for natural transformation in streptococci

L Fontaine, A Wahl, M Fléchard, J Mignolet… - Infection, Genetics and …, 2015 - Elsevier
Natural DNA transformation is a lateral gene transfer mechanism during which bacteria take
up naked DNA from their environment and stably integrate it in their genome. The proteins …

Community interactions of oral streptococci

NS Jakubovics, SA Yassin, AH Rickard - Advances in applied microbiology, 2014 - Elsevier
It is now clear that the most common oral diseases, dental caries and periodontitis, are
caused by mixed-species communities rather than by individual pathogens working in …

Biochemical features of beneficial microbes: foundations for therapeutic microbiology

MA Engevik, J Versalovic - Microbiology spectrum, 2017 - Am Soc Microbiol
Commensal and beneficial microbes secrete myriad products which target the mammalian
host and other microbes. These secreted substances aid in bacterial niche development …

Comprehensive analysis of bacteriocins in Streptococcus mutans

A Watanabe, M Kawada-Matsuo, MNT Le… - Scientific reports, 2021 - nature.com
Streptococcus mutans produces bacteriocins that show antibacterial activity against several
bacteria. However, comprehensive analysis of these bacteriocins has not been well done. In …

[HTML][HTML] For the greater good: Programmed cell death in bacterial communities

SH Peeters, MI de Jonge - Microbiological research, 2018 - Elsevier
For a long a time programmed cell death was thought to be a unique characteristic of higher
eukaryotes, but evidence has accumulated showing that programmed cell death is a …