COVID‐19 therapy with mesenchymal stromal cells (MSC) and convalescent plasma must consider exosome involvement: Do the exosomes in convalescent plasma …
PW Askenase - Journal of extracellular vesicles, 2020 - Wiley Online Library
Exosome extracellular vesicles as biologic therapy for COVID‐19 are discussed for two
areas. The first involves the growing use of mesenchymal stromal cells (MSCs) for the …
areas. The first involves the growing use of mesenchymal stromal cells (MSCs) for the …
[HTML][HTML] Inhibitory immune checkpoint molecules and exhaustion of T cells in COVID-19
M Barnova, A Bobcakova, V Urdova… - Physiological …, 2021 - ncbi.nlm.nih.gov
Summary COVID-19 (Coronavirus Disease) is an infectious disease caused by the
coronavirus SARS-CoV-2 (Severe acute respiratory syndrome Coronavirus 2), which …
coronavirus SARS-CoV-2 (Severe acute respiratory syndrome Coronavirus 2), which …
Analysis of Co-inhibitory Receptor Expression in COVID-19 Infection Compared to Acute Plasmodium falciparum Malaria: LAG-3 and TIM-3 Correlate With T Cell …
M Herrmann, S Schulte, NH Wildner, M Wittner… - Frontiers in …, 2020 - frontiersin.org
Coronavirus disease 2019 (COVID-19) which is caused by the novel SARS-CoV-2 virus is a
severe flu-like illness which is associated with hyperinflammation and immune dysfunction …
severe flu-like illness which is associated with hyperinflammation and immune dysfunction …
Immunomodulatory properties of immune checkpoint inhibitors—more than boosting T-cell responses?
Simple Summary Tumor immune evasion is mediated in large part by the inhibition of anti-
tumor T cell responses. Both the induction of tumor antigen-specific T cells and the activation …
tumor T cell responses. Both the induction of tumor antigen-specific T cells and the activation …
Mouse models for unravelling immunology of blood stage malaria
AC Olatunde, DH Cornwall, M Roedel, TJ Lamb - Vaccines, 2022 - mdpi.com
Malaria comprises a spectrum of disease syndromes and the immune system is a major
participant in malarial disease. This is particularly true in relation to the immune responses …
participant in malarial disease. This is particularly true in relation to the immune responses …
Exhausted PD-1+ TOX+ CD8+ T Cells Arise Only in Long-Term Experimental Trypanosoma cruzi Infection
Infection with Trypanosoma cruzi remains the most important neglected zoonosis in Latin
America. This infection does not lead to specific symptoms in the acute phase, but chronic …
America. This infection does not lead to specific symptoms in the acute phase, but chronic …
Increased Expression of Multiple Co-Inhibitory Molecules on Malaria-Induced CD8+ T Cells Are Associated With Increased Function Instead of Exhaustion
Activated cytotoxic CD8+ T cells can selectively kill target cells in an antigen-specific
manner. However, their prolonged activation often has detrimental effects on tissue …
manner. However, their prolonged activation often has detrimental effects on tissue …
Synergistic blockade of TIGIT and PD-L1 increases type-1 inflammation and improves parasite control during murine blood-stage Plasmodium yoelii non-lethal …
RS Dookie, A Villegas-Mendez… - Infection and …, 2024 - journals.asm.org
Pro-inflammatory immune responses are rapidly suppressed during blood-stage malaria but
the molecular mechanisms driving this regulation are still incompletely understood. In this …
the molecular mechanisms driving this regulation are still incompletely understood. In this …
Chronic malaria exposure is associated with inhibitory markers on T cells that correlate with atypical memory and marginal zone-like B cells
RA Mitchell, I Ubillos, P Requena… - Clinical and …, 2024 - academic.oup.com
Chronic immune activation from persistent malaria infections can induce immunophenotypic
changes associated with T-cell exhaustion. However, associations between T and B cells …
changes associated with T-cell exhaustion. However, associations between T and B cells …
Increased pathogenicity and pro-inflammatory capabilities of mucosal-associated invariant T cells involved in Oral Lichen Planus
S Chen, X Wu, Y Yang, X Xu, X Xiong, W Meng - BMC Oral Health, 2024 - Springer
Background Mucosal-associated invariant T (MAIT) cells assume pivotal roles in numerous
autoimmune inflammatory maladies. However, scant knowledge exists regarding their …
autoimmune inflammatory maladies. However, scant knowledge exists regarding their …