Synthesis of cinnamic acid derivatives and leishmanicidal activity against Leishmania braziliensis

MP Rodrigues, DC Tomaz, LA de Souza… - European journal of …, 2019 - Elsevier
Leishmania braziliensis is one of the pathogenic agents of cutaneous and mucocutanoeous
leishmaniasis. There are no validated vaccines to prevent the infection and the treatment …

Eugenol derivatives with 1, 2, 3-triazole moieties: Oral treatment of cutaneous leishmaniasis and a quantitative structure-activity relationship model for their …

RR Teixeira, PAR Gazolla, MPG Borsodi… - Experimental …, 2022 - Elsevier
Leishmaniasis is a group of neglected vector-borne tropical diseases caused by protozoan
parasites of the genus Leishmania that multiply within phagocytic cells and have a wide …

Copper/Palladium Bimetallic System for the Synthesis of Isobenzofuranones through [4+ 1] Annulation between Propiophenones and Benzoic Acids

X Liang, M Xiong, H Zhu, K Shi, Y Zhou, Y Pan - Organic Letters, 2020 - ACS Publications
A copper/palladium-catalyzed annulation from benzoic acids and propiophenones for the
synthesis of isobenzofuranones was reported. The Cu-(2, 2, 6, 6-tetramethylpiperidin-1-yl) …

Leishmanicidal activity and 4D quantitative structure–activity relationship and molecular docking studies of vanillin-containing 1, 2, 3-triazole derivatives

PA Rodrigues Gazolla, WP Lima… - Future Medicinal …, 2024 - Taylor & Francis
Aim: The assessment of the antileishmanial potential of 22 vanillin-containing 1, 2, 3-triazole
derivatives against Leishmania braziliensis is reported. Materials & methods: Initial …

Efficient PhB (OH) 2-catalyzed one-pot synthesis of 3-substituted isoindolin-1-ones and isobenzofuran-1 (3H)-ones under solvent free conditions

A Palillero-Cisneros, M Bedolla-Medrano, M Ordóñez - Tetrahedron, 2018 - Elsevier
An efficient and practical one-pot synthesis of 3-substituted isoindolin-1-ones and
isobenzofuran-1 (3H)-ones has been developed under solvent free-conditions using non …

[HTML][HTML] The therapeutic potential of novel isobenzofuranones against Naegleria fowleri

A Rizo-Liendo, I Arberas-Jiménez, I Sifaoui… - International Journal for …, 2021 - Elsevier
Abstract The Free-Living Amoeba species, Naegleria fowleri is the causative agent of a
lethal encephalitis known as Primary Amoebic Encephalitis (PAM). Moreover, most of the …

[HTML][HTML] Isobenzofuran-1 (3H)-one derivatives: Amoebicidal activity and program cell death in Acanthamoeba castellanii Neff

RL Rodríguez-Expósito, M Reyes-Batlle… - Biomedicine & …, 2022 - Elsevier
The genus Acanthamoeba is characterized by being a group of ubiquitous and free-living
amoebae that inhabit a variety of environments. Generally, human infections by this parasite …

Preparation of NaNbO3 nanoplates and their application in the synthesis of arylidene indan-1,3-diones, functionalized C-3 isobenzofuranones and Meldrum's acid …

SF da Silva, FA Silva, APM de Souza… - Journal of Materials …, 2022 - Springer
The present investigation describes the preparation of a sodium niobate nanostructured
material and the application of it as catalyst in condensation reactions. Well-defined NaNbO …

Association of electroanalytical and spectrophotometric methods to evaluate the antioxidant activity of isobenzofuranone in primary cultures of hippocampal neurons

A dos Reis Teixeira, RR Teixeira, IML Ribeiro… - Toxicology in Vitro, 2020 - Elsevier
Abstract The isobenzofuran-1 (3H)-ones (phthalides) exhibit various biological activities,
including antioxidant activity on reactive oxygen species (ROS). An excess of ROS that …

[PDF][PDF] Green Synthesis: A Novel Method for Bromination of 7-AminoPhthalide

SR Gondi - 2021 - chemrxiv.org
A novel method for preparing a bromo substituted 7-Amino-phthalides and 7-Amino-3-
hydroxy-phthalides via the bromonium ion intermediate under acidic conditions athigher …