Prions: protein aggregation and infectious diseases

A Aguzzi, AM Calella - Physiological reviews, 2009 - journals.physiology.org
Transmissible spongiform encephalopathies (TSEs) are inevitably lethal neurodegenerative
diseases that affect humans and a large variety of animals. The infectious agent responsible …

Sensitivity analysis practices: Strategies for model-based inference

A Saltelli, M Ratto, S Tarantola, F Campolongo… - Reliability engineering & …, 2006 - Elsevier
Fourteen years after Science's review of sensitivity analysis (SA) methods in 1989 (System
analysis at molecular scale, by H. Rabitz) we search Science Online to identify and then …

[HTML][HTML] Environmental sources of prion transmission in mule deer

MW Miller, ES Williams, NT Hobbs… - Emerging infectious …, 2004 - ncbi.nlm.nih.gov
Whether transmission of the chronic wasting disease (CWD) prion among cervids requires
direct interaction with infected animals has been unclear. We report that CWD can be …

Two-stage effects of awareness cascade on epidemic spreading in multiplex networks

Q Guo, X Jiang, Y Lei, M Li, Y Ma, Z Zheng - Physical Review E, 2015 - APS
Human awareness plays an important role in the spread of infectious diseases and the
control of propagation patterns. The dynamic process with human awareness is called …

Disease dynamics over very different time-scales: foot-and-mouth disease and scrapie on the network of livestock movements in the UK

RR Kao, DM Green, J Johnson… - Journal of the Royal …, 2007 - royalsocietypublishing.org
We analyse the relationship between the network of livestock movements in the UK and the
dynamics of two diseases: foot-and-mouth disease (FMD), which has an incubation period of …

Update on classical and atypical scrapie in sheep and goats

JJ Greenlee - Veterinary pathology, 2019 - journals.sagepub.com
Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) or prion
disease of sheep and goats. Scrapie is a protein misfolding disease where the normal prion …

[图书][B] The human brain during the second trimester

SA Bayer, J Altman - 2005 - books.google.com
The brain in the second trimester, the subject of Volume 3, is nearing anatomical maturity
throughout the brainstem. In contrast, the neurogenesis and neuronal migration are still in …

PrPSc accumulation in myocytes from sheep incubating natural scrapie

O Andréoletti, S Simon, C Lacroux, N Morel… - Nature medicine, 2004 - nature.com
Abstract Because variant Creutzfeldt–Jakob disease (vCJD) in humans probably results
from consumption of products contaminated with tissue from animals with bovine spongiform …

A descriptive study of the prevalence of atypical and classical scrapie in sheep in 20 European countries

A Fediaevsky, SC Tongue, M Nöremark… - BMC veterinary …, 2008 - Springer
Background The development of active surveillance programmes for transmissible
spongiform encephalopathies of small ruminants across Europe has led to the recent …

BSE in sheep bred for resistance to infection

F Houston, W Goldmann, A Chong, M Jeffrey… - Nature, 2003 - nature.com
Selective breeding for disease-resistant genotypes is being pursued as a means of
eradicating scrapie (and bovine spongiform encephalopathy (BSE), if it is present) from …