Effect of thyroid hormones on neurons and neurodevelopment

G Prezioso, C Giannini, F Chiarelli - Hormone research in paediatrics, 2018 - karger.com
This review focuses on the current knowledge of the effects of thyroid hormones on central
nervous system differentiation and development in animals and the human fetal brain. The …

Disruption in thyroid signaling pathway: a mechanism for the effect of endocrine-disrupting chemicals on child neurodevelopment

A Ghassabian, L Trasande - Frontiers in endocrinology, 2018 - frontiersin.org
Thyroid hormones are crucial in normal brain development. Transient and mild thyroid
hormone insufficiency in pregnancy is also associated with impaired neurodevelopment in …

Maternal thyroid function during pregnancy and child brain morphology: a time window-specific analysis of a prospective cohort

TA Jansen, TIM Korevaar, TA Mulder… - The lancet Diabetes & …, 2019 - thelancet.com
Background Adequate thyroid hormone availability during pregnancy is necessary for
optimal fetal brain development. During the first 18–20 weeks of gestation, fetal thyroid …

Maternal hormonal milieu influence on fetal brain development

A Miranda, N Sousa - Brain and behavior, 2018 - Wiley Online Library
An adverse maternal hormonal environment during pregnancy can be associated with
abnormal brain growth. Subtle changes in fetal brain development have been observed …

Maternal thyroid hormone insufficiency during pregnancy and risk of neurodevelopmental disorders in offspring: A systematic review and meta‐analysis

W Thompson, G Russell, G Baragwanath… - Clinical …, 2018 - Wiley Online Library
Background In the last 2 decades, several studies have examined the association between
maternal thyroid hormone insufficiency during pregnancy and neurodevelopmental …

Neurostructural traces of early life adversities: A meta-analysis exploring age-and adversity-specific effects

TM Pollok, A Kaiser, EJ Kraaijenvanger… - Neuroscience & …, 2022 - Elsevier
Early life adversities (ELAs) are associated with an increased risk of psychopathology, with
studies suggesting a relation to structural brain alterations. Given the recently growing …

Thyroid function and thyroid disorders during pregnancy: a review and care pathway

AP Delitala, G Capobianco, PL Cherchi… - Archives of gynecology …, 2019 - Springer
Purpose To review the literature on thyroid function and thyroid disorders during pregnancy.
Methods A detailed literature research on MEDLINE, Cochrane library, EMBASE, NLH …

Clinical associations of maternal thyroid function with foetal brain development: epidemiological interpretation and overview of available evidence

TIM Korevaar, H Tiemeier, RP Peeters - Clinical Endocrinology, 2018 - Wiley Online Library
Thyroid hormone is an important regulator of early brain development, particularly during
early stages of gestation during which foetal thyroid hormone availability depends on the …

Iodine Deficiency, Maternal Hypothyroxinemia and Endocrine Disrupters Affecting Fetal Brain Development: A Scoping Review

R Grossklaus, KP Liesenkötter, K Doubek, H Völzke… - Nutrients, 2023 - mdpi.com
This scoping review critically discusses the publications of the last 30 years on the impact of
mild to moderate iodine deficiency and the additional impact of endocrine disrupters during …

Congenital hypothyroidism and brain development: association with other psychiatric disorders

K Uchida, M Suzuki - Frontiers in neuroscience, 2021 - frontiersin.org
Thyroid hormones play an important role in brain development, and thyroid hormone
insufficiency during the perinatal period results in severe developmental delays. Perinatal …