Extended spectrum beta-lactamases (ESBLs) are defined as enzymes produced by certain
bacteria that are able to hydrolyze extended spectrum cephalosporin. They are therefore …

Extended-spectrum β-lactamases (ESBLs) are a rapidly evolving group of β-lactamases
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …

Extended-spectrum β-lactamases (ESBLs) are a group of plasmid-mediated, diverse,
complex and rapidly evolving enzymes that are posing a major therapeutic challenge today …

SUMMARY β-Lactamases continue to be the leading cause of resistance to β-lactam
antibiotics among gram-negative bacteria. In recent years there has been an increased …

ABSTRACT A multilocus sequence typing (MLST) scheme was developed for Klebsiella
pneumoniae. Sequences of seven housekeeping genes were obtained for 67 K …

The emergence and spread of resistance in Enterobacteriaceae are complicating the
treatment of serious nosocomial infections and threatening to create species resistant to all …

The increased use of fluoroquinolones has led to increasing resistance to these
antimicrobials, with rates of resistance that vary by both organism and geographic region …

The β-lactamases are the major bacterial defense of gram-negative bacteria against β-
lactam antibiotics. This review details the many types of β-lactamases, explains how they …

Objectives To study the comparative mortality associated with carbapenems and alternative
antibiotics for the treatment of patients with extended-spectrum β-lactamase (ESBL)-positive …

Fluoroquinolone resistance is emerging in Gram-negative pathogens worldwide. The
traditional understanding that quinolone resistance is acquired only through mutation and …