We review, systematize and discuss models of diffusion in neuronal tissue, by putting them into an overarching physical context of coarse‐graining over an increasing diffusion length …
The first phase of the Human Connectome Project pioneered advances in MRI technology for mapping the macroscopic structural connections of the living human brain through the …
Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the timing and synchronization of neural activation. Noninvasive measurement of axon radii …
Biophysical models of diffusion in white matter have been center-stage over the past two decades and are essentially based on what is now commonly referred to as the “Standard …
IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25 years. In this review, we dwell on the various challenges along the journey of bringing a …
Biophysical modeling of macroscopic diffusion-weighted MRI signal in terms of microscopic cellular parameters holds the promise of quantifying the integrity of white matter …
We develop a general analytical and numerical framework for estimating intra-and extra- neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion …
Abstract Development of therapies for neurological disorders depends on our ability to non- invasively diagnose and monitor the progression of underlying pathologies at the cellular …
How does a systematic time-dependence of the diffusion coefficient D (t) affect the ergodic and statistical characteristics of fractional Brownian motion (FBM)? Here, we answer this …