On modeling

DS Novikov, VG Kiselev… - Magnetic resonance in …, 2018 - Wiley Online Library
Mapping tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

[HTML][HTML] Connectome 2.0: Developing the next-generation ultra-high gradient strength human MRI scanner for bridging studies of the micro-, meso-and macro …

SY Huang, T Witzel, B Keil, A Scholz, M Davids, P Dietz… - NeuroImage, 2021 - Elsevier
The first phase of the Human Connectome Project pioneered advances in MRI technology
for mapping the macroscopic structural connections of the living human brain through the …

Noninvasive quantification of axon radii using diffusion MRI

J Veraart, D Nunes, U Rudrapatna, E Fieremans… - elife, 2020 - elifesciences.org
Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the
timing and synchronization of neural activation. Noninvasive measurement of axon radii …

[HTML][HTML] Neurite Exchange Imaging (NEXI): A minimal model of diffusion in gray matter with inter-compartment water exchange

IO Jelescu, A de Skowronski, F Geffroy, M Palombo… - NeuroImage, 2022 - Elsevier
Biophysical models of diffusion in white matter have been center-stage over the past two
decades and are essentially based on what is now commonly referred to as the “Standard …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

TE dependent Diffusion Imaging (TEdDI) distinguishes between compartmental T2 relaxation times

J Veraart, DS Novikov, E Fieremans - NeuroImage, 2018 - Elsevier
Biophysical modeling of macroscopic diffusion-weighted MRI signal in terms of microscopic
cellular parameters holds the promise of quantifying the integrity of white matter …

Rotationally-invariant mapping of scalar and orientational metrics of neuronal microstructure with diffusion MRI

DS Novikov, J Veraart, IO Jelescu, E Fieremans - NeuroImage, 2018 - Elsevier
We develop a general analytical and numerical framework for estimating intra-and extra-
neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion …

On the scaling behavior of water diffusion in human brain white matter

J Veraart, E Fieremans, DS Novikov - NeuroImage, 2019 - Elsevier
Abstract Development of therapies for neurological disorders depends on our ability to non-
invasively diagnose and monitor the progression of underlying pathologies at the cellular …

Anomalous diffusion, aging, and nonergodicity of scaled Brownian motion with fractional Gaussian noise: Overview of related experimental observations and models

W Wang, R Metzler, AG Cherstvy - Physical Chemistry Chemical …, 2022 - pubs.rsc.org
How does a systematic time-dependence of the diffusion coefficient D (t) affect the ergodic
and statistical characteristics of fractional Brownian motion (FBM)? Here, we answer this …