Apolipoprotein B and cardiovascular disease: biomarker and potential therapeutic target

J Behbodikhah, S Ahmed, A Elyasi, LJ Kasselman… - Metabolites, 2021 - mdpi.com
Apolipoprotein (apo) B, the critical structural protein of the atherogenic lipoproteins, has two
major isoforms: apoB48 and apoB100. ApoB48 is found in chylomicrons and chylomicron …

Atherosclerosis development and progression: the role of atherogenic small, dense LDL

J Vekic, A Zeljkovic, AFG Cicero, A Janez, AP Stoian… - Medicina, 2022 - mdpi.com
Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It
has been shown over the last decades that the reduction of atherosclerotic progression is a …

The atherogenic role of circulating modified lipids in atherosclerosis

VI Summerhill, AV Grechko, SF Yet, IA Sobenin… - International journal of …, 2019 - mdpi.com
Lipid accumulation in the arterial wall is a crucial event in the development of atherosclerotic
lesions. Circulating low-density lipoprotein (LDL) is the major source of lipids that …

A metabolic view on menopause and ageing

K Auro, A Joensuu, K Fischer, J Kettunen… - Nature …, 2014 - nature.com
The ageing of the global population calls for a better understanding of age-related metabolic
consequences. Here we report the effects of age, sex and menopause on serum metabolites …

Small dense low-density lipoprotein: Analytical review

C Kanonidou - Clinica Chimica Acta, 2021 - Elsevier
Background The causal relationship between low-density lipoprotein (LDL) and
atherosclerotic cardiovascular disease (CVD) has been firmly substantiated. LDL consists of …

LDL and HDL subclasses in acute ischemic stroke: prediction of risk and short-term mortality

A Zeljkovic, J Vekic, V Spasojevic-Kalimanovska… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: Small, dense low-density lipoprotein (sdLDL) and small-sized high-density
lipoprotein (HDL) particles are established risk factors for ischemic heart disease. However …

Novel and traditional lipid profiles in Metabolic Syndrome reveal a high atherogenicity

S Paredes, L Fonseca, L Ribeiro, H Ramos… - Scientific reports, 2019 - nature.com
Low-density-lipoprotein cholesterol (LDL-c) guides lipid-lowering therapy, although other
lipid parameters could better reflect cardiovascular disease (CVD) risk. Discordance …

Correlation between small dense low-density lipoprotein cholesterol and carotid artery intima-media thickness in a healthy Chinese population

H Shen, L Xu, J Lu, T Hao, C Ma, H Yang, Z Lu… - Lipids in health and …, 2015 - Springer
Background Small dense low-density lipoprotein cholesterol (sdLDL-C) concentration was
useful in the assessment of the presence of cardiovascular diseases (CVD) and its severity …

Usefulness of the LDL-C/apoB ratio in the overall evaluation of atherogenicity of lipid profile

AM Kaneva, NN Potolitsyna… - Archives of physiology and …, 2017 - Taylor & Francis
Context: The ratio of low-density lipoprotein cholesterol to apolipoprotein-B (LDL-C/apoB)
conventionally represents an alternative index of LDL particle size. Objective: This study was …

Lower serum triglyceride levels linked to more severe motor performance in Parkinson's disease

M Zhang, H Chen, G Liu, X Wang, Z Wang, T Feng… - Neurological …, 2022 - Springer
Introduction Emerging evidence has suggested that lipid metabolism is correlated with
Parkinson's disease (PD) onset and progression. However, the effect of lipid metabolism on …