Analysis of sequence diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP-1)

LH Miller, T Roberts, M Shahabuddin… - Molecular and …, 1993 - Elsevier
Immunization with the first identified Plasmodium falciparum merozoite surface protein (MSP-
1) protected monkeys from an otherwise fatal infection. The question of whether the high …

Merozoite surface antigen-I of Plasmodium

JA Cooper - Parasitology Today, 1993 - cell.com
The merozoite is the invasive form of the asexual stage of Plasmodium species. At least two
polymorphic glycoproteins have been found on its surface in the human malaria parasite …

Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum

AA Escalante, AA Lal, FJ Ayala - Genetics, 1998 - academic.oup.com
We have studied the genetic polymorphism at 10 Plasmodium falciparum loci that are
considered potential targets for specific antimalarial vaccines. The polymorphism is …

A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan

DR Cavanagh, IM Elhassan, C Roper… - The Journal of …, 1998 - journals.aai.org
Abstract Merozoite surface protein-1 (MSP-1) of Plasmodium falciparum is a malaria vaccine
candidate Ag. Immunity to MSP-1 has been implicated in protection against infection in …

A recombinant baculovirus 42-kilodalton C-terminal fragment of Plasmodium falciparum merozoite surface protein 1 protects Aotus monkeys against malaria

SP Chang, SE Case, WL Gosnell… - Infection and …, 1996 - Am Soc Microbiol
The immunogenicity and protective efficacy of baculovirus recombinant polypeptide based
on the Plasmodium falciparum merozoite surface protein 1 (MSP-1) has been evaluated in …

[HTML][HTML] Polymorphic antigens in Plasmodium falciparum

RF Anders, JA Smythe - Blood, 1989 - Elsevier
A PROMINENT FEATURE of host responses to infection with malaria parasites is an
antibody response that includes specificities to a large number of different protein antigens …

Invasion-inhibitory antibodies inhibit proteolytic processing of apical membrane antigen 1 of Plasmodium falciparum merozoites

S Dutta, JD Haynes, JK Moch… - Proceedings of the …, 2003 - National Acad Sciences
Apical membrane antigen 1 (AMA-1) is a promising vaccine candidate for Plasmodium
falciparum malaria. Antibodies against AMA-1 of P. falciparum (PfAMA-1) interrupt merozoite …

NYVAC-Pf7: a poxvirus-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria

JA Tine, DE Lanar, DM Smith, BT Wellde… - Infection and …, 1996 - Am Soc Microbiol
The highly attenuated NYVAC vaccinia virus strain has been utilized to develop a
multiantigen, multistage vaccine candidate for malaria, a disease that remains a serious …

The epidemiology of multiple-clone Plasmodium falciparum infections in Gambian patients

DJ Conway, BM Greenwood, JS McBride - Parasitology, 1991 - cambridge.org
The occurrence of multiple-clone Plasmodium falciparum haploid blood-stage infections is a
pre-requisite for cross-fertilization and genetic exchange at the diploid stage in the mosquito …

[HTML][HTML] The crystal structure of C-terminal merozoite surface protein 1 at 1.8 Å resolution, a highly protective malaria vaccine candidate

V Chitarra, I Holm, GA Bentley, S Pêtres, S Longacre - Molecular cell, 1999 - cell.com
The C-terminal proteolytic processing product of merozoite surface protein 1 (MSP1)
appears essential for successful erythrocyte invasion by the malarial parasite, Plasmodium …