[HTML][HTML] Hematopoietic versus leukemic stem cell quiescence: Challenges and therapeutic opportunities

E O'Reilly, HA Zeinabad, E Szegezdi - Blood Reviews, 2021 - Elsevier
Hematopoietic stem cells (HSC) are responsible for the production of mature blood cells. To
ensure that the HSC pool does not get exhausted over the lifetime of an individual, most …

[HTML][HTML] Transcriptional reprogramming of distinct peripheral sensory neuron subtypes after axonal injury

W Renthal, I Tochitsky, L Yang, YC Cheng, E Li… - Neuron, 2020 - cell.com
Primary somatosensory neurons are specialized to transmit specific types of sensory
information through differences in cell size, myelination, and the expression of distinct …

The MyoGravity project to study real microgravity effects on human muscle precursor cells and tissue

ES Di Filippo, S Chiappalupi, S Falone, V Dolo… - npj …, 2024 - nature.com
Microgravity (µG) experienced during space flights promotes adaptation in several
astronauts' organs and tissues, with skeletal muscles being the most affected. In response to …

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

SK Merid, A Novoloaca, GC Sharp, LK Küpers… - Genome medicine, 2020 - Springer
Background Preterm birth and shorter duration of pregnancy are associated with increased
morbidity in neonatal and later life. As the epigenome is known to have an important role …

Proteomic architecture of valvular extracellular matrix: FNDC1 and MXRA5 are new biomarkers of aortic stenosis

R Bouchareb, S Guauque-Olarte, J Snider… - Basic to Translational …, 2021 - jacc.org
This study analyzed the expression of extracellular matrix (ECM) proteins during aortic valve
calcification with mass spectrometry, and further validated in an independent human cohort …

[HTML][HTML] A single-cell transcriptome of mesenchymal stromal cells to fabricate bioactive hydroxyapatite materials for bone regeneration

P Guo, X Liu, P Zhang, Z He, Z Li, M Alini… - Bioactive Materials, 2022 - Elsevier
The osteogenic microenvironment of bone-repairing materials plays a key role in
accelerating bone regeneration but remains incompletely defined, which significantly limits …

White matter stroke induces a unique oligo-astrocyte niche that inhibits recovery

EG Sozmen, DJ DiTullio, S Rosenzweig… - Journal of …, 2019 - Soc Neuroscience
Subcortical white matter stroke is a common stroke subtype. White matter stroke stimulates
adjacent oligodendrocyte progenitor cells (OPCs) to divide and migrate to the lesion, but …

Compartment-resolved proteomic analysis of mouse aorta during atherosclerotic plaque formation reveals osteoclast-specific protein expression

M Wierer, M Prestel, HB Schiller, G Yan… - Molecular & Cellular …, 2018 - ASBMB
Atherosclerosis leads to vascular lesions that involve major rearrangements of the vascular
proteome, especially of the extracellular matrix (ECM). Using single aortas from ApoE knock …

Bio‐derived hydroxystearic acid ameliorates skin age spots and conspicuous pores

R Schütz, AV Rawlings, E Wandeler… - … Journal of Cosmetic …, 2019 - Wiley Online Library
Introduction We report on the preparation and efficacy of 10‐hydroxystearic acid (HSA) that
improves facial age spots and conspicuous pores. Methods The hydration of oleic acid into …

[HTML][HTML] Anti-PD-L1 therapy altered inflammation but not survival in a lethal murine hepatitis virus-1 pneumonia model

CS Curran, X Cui - Frontiers in Immunology, 2024 - frontiersin.org
Introduction Because prior immune checkpoint inhibitor (ICI) therapy in cancer patients
presenting with COVID-19 may affect outcomes, we investigated the beta-coronavirus …