Elucidation of the physiologically distinct subunits of troponin in 1973 greatly facilitated our
understanding of cardiac contraction. Although troponins are expressed in both skeletal and …

Abstract BACKGROUND Cardiac troponins I (cTnI) and T (cTnT) have received international
endorsement as the standard biomarkers for detection of myocardial injury, for risk …

Background: We assessed whether plasma troponin I measured by a high-sensitivity assay
(hs-TnI) is associated with incident cardiovascular disease (CVD) and mortality in a …

Abstract Cardiac miRNAs (miR-1, miR133a, miR-208a/b, and miR-499) are abundantly
expressed in the myocardium. They play a central role in cardiogenesis, heart function and …

Importance Lack of objective biomarkers for brain damage hampers acute diagnosis and
clinical decision making about return to play after sports-related concussion. Objectives To …

The release of cardiomyocyte components, ie biomarkers, into the bloodstream in higher
than usual quantities indicates an ongoing pathological process. Thus, detection of elevated …

Regular physical exercise is recommended for the primary prevention of cardiovascular
disease. Although the high prevalence of physical inactivity remains a formidable public …

It has been known for 50 years that transaminase activity increases in patients with acute
myocardial infarction. With the development of creatine kinase (CK), biomarkers of cardiac …

Recently, the European Society of Cardiology (ESC) and the American College of
Cardiology (ACC) convened a conference to discuss refinements in the diagnosis of acute …

Abstract The Sixth Conference on the “Standards of Laboratory Practice Series”, sponsored
by the National Academy of Clinical Biochemistry (NACB), was held on August 4–5, 1998, at …