The purpose of this review is to summarize essential pharmacological, pharmaceutical, and
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …

The use of nitroglycerin in the treatment of angina pectoris began not long after its original
synthesis in 1847. Since then, the discovery of nitric oxide as a biological effector and better …

Background Morbidity and mortality in pulmonary arterial hypertension (PAH) remain high.
Activation of platelet-derived growth factor receptor, colony stimulating factor 1 receptor, and …

Defective regulation of the Janus kinase-signal transducer and activator of transcription (JAK-
STAT) signalling pathway in cancers, haematological diseases, and chronic inflammatory …

Microalgae are single-cell, photosynthetic organisms whose biodiversity places them at the
forefront of biological producers of high-value molecules including lipids and pigments …

Pulmonary hypertension (PH), previously defined as a mean pulmonary artery pressure of
greater than 25 mm Hg, has recently been redefined by the Sixth World Symposium on …

Methods We identified non-intubated Covid-19 patients who received iNO therapy. The
study was approved by the Institutional Review Board of Boston Medical Center and the …

Nitric oxide (NO) is a powerful biological mediator provided with a number of activities of
relevance for the prevention of thrombosis, like vasodilation, inhibition of platelet adhesion …

Lungs are important respiratory organs primarily involved in gas exchange. Lungs interact
directly with the environment and their primary function is affected by several inflammatory …

Over the last two decades, developments in nanomedicine have resulted in technical
advances with application to clinical science. Both organic and inorganic nanoparticles …