Evolution of cell therapy for renal cell carcinoma

Y Wang, ER Suarez, G Kastrunes, NSP de Campos… - Molecular Cancer, 2024 - Springer
Abstract Treatment for renal cell carcinoma (RCC) has improved dramatically over the last
decade, shifting from high-dose cytokine therapy in combination with surgical resection of …

Novel Immune Therapies for Renal Cell Carcinoma: Looking Beyond the Programmed Cell Death Protein 1 and Cytotoxic T-Lymphocyte-Associated Protein 4 Axes

E Saad, RM Saliby, C Labaki, W Xu… - Hematology …, 2023 - hemonc.theclinics.com
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Affinity fine-tuning anti-CAIX CAR-T cells mitigate on-target off-tumor side effects

Y Wang, A Buck, B Piel, L Zerefa, N Murugan… - Molecular Cancer, 2024 - Springer
One of the major hurdles that has hindered the success of chimeric antigen receptor (CAR) T
cell therapies against solid tumors is on-target off-tumor (OTOT) toxicity due to sharing of the …

The 5th Kidney Cancer Research Summit: Research Accelerating Cures for Renal Cell Carcinoma in 2023

TK Choueiri, SK Pal, B Lewis, S Poteat, K Pels… - The …, 2024 - academic.oup.com
Abstract The 5th Kidney Cancer Research Summit was a hybrid event hosted in Boston, MA
in July 2023. As in previous editions, the conference attracted a wide representation of …

Achievements, Challenges, And Limitations Of Car-T Cell Therapy In Cancer Treatment, A Comprehensive Review

A Tahavvori, F Alizadeh, A Mousavian… - Journal of …, 2022 - pnrjournal.com
Chimeric antigen receptor (CAR)-T cell is a novel and promising therapy strategy for
numerous malignant neoplasms management, specifically relapsing or refractory B cell …

[HTML][HTML] Engineered T-Cell Therapy: The Next Direction for RCC Immuno-oncology?

JJH Zhang, NA Patel, A Drakaki, AJ Pantuck - kidney-cancer-journal.com
Synthetic biology in the form of engineered antigen specific T-cells for cancer
immunotherapy has demonstrated its potential to revolutionize cancer treatment. However …