Anticancer peptides mechanisms, simple and complex

P Norouzi, M Mirmohammadi, MHH Tehrani - Chemico-Biological …, 2022 - Elsevier
Peptide therapy has started since 1920s with the advent of insulin application, and now it
has emerged as a new approach in treatment of diseases including cancer. Using anti …

Folate decorated epigallocatechin-3-gallate (EGCG) loaded PLGA nanoparticles; in-vitro and in-vivo targeting efficacy against MDA-MB-231 tumor xenograft

J Kazi, R Sen, S Ganguly, T Jha, S Ganguly… - International Journal of …, 2020 - Elsevier
Abstract Epigallocatechin-3-gallate (EGCG), a major polyphenolic constituent of green tea
exhibits significant anti-cancer potential over a wide range of cancer cells. We have …

Apigenin-loaded PLGA-DMSA nanoparticles: a novel strategy to treat melanoma lung metastasis

R Sen, S Ganguly, S Ganguly, MC Debnath… - Molecular …, 2021 - ACS Publications
The flavone apigenin (APG), alone as well as in combination with other chemotherapeutic
agents, is known to exhibit potential anticancer effects in various tumors and inhibit growth …

Nanoencapsulated betulinic acid analogue distinctively improves colorectal carcinoma in vitro and in vivo

D Dutta, B Paul, B Mukherjee, L Mondal, S Sen… - Scientific reports, 2019 - nature.com
Betulinic acid, a plant secondary metabolite, has gained significant attention due to its
antiproliferative activity over a range of cancer cells. A promising betulinic acid analogue …

Design of 5-fluorouracil (5-FU) loaded, folate conjugated peptide linked nanoparticles, a potential new drug carrier for selective targeting of tumor cells

J Kazi, R Mukhopadhyay, R Sen, T Jha, S Ganguly… - …, 2019 - pubs.rsc.org
In the present investigation folate peptide (FA-Pep) conjugated 5-fluorouracil (5-FU) loaded
nanoparticles were synthesized and their tumor targeting potentiality was monitored by …

Inhibitory potential of iRGD peptide-conjugated garcinol-loaded biodegradable nanoparticles in rat colorectal carcinoma

B Paul, RH Gaonkar, D Dutta, R Dasi, B Mukherjee… - Biomaterials …, 2022 - Elsevier
Targeted drug delivery has become attention in chemotherapy during the last decade. The
principle of chemotherapy seeks maximum effect to the desired site and the minimum impact …

Intrinsically fluorescent oligomeric cytotoxic conjugates toxic for FGFR1-overproducing cancers

N Porębska, A Knapik, M Poźniak… - …, 2021 - ACS Publications
Fibroblast growth factor receptor 1 (FGFR1) is an integral membrane protein that transmits
prolife signals through the plasma membrane. Overexpression of FGFR1 has been reported …

Multifunctional self-assembled peptide nanoparticles for multimodal imaging-guided enhanced theranostic applications against glioblastoma multiforme

SFA Rizvi, A Ali, M Ahmad, S Mu, H Zhang - Nanoscale Advances, 2021 - pubs.rsc.org
The synthesis of self-assembled peptide nanoparticles using a facile one-pot synthesis
approach is gaining increasing attention, allowing therapy in combination with diagnosis …

Dual drug co‐encapsulation of bevacizumab and pemetrexed clocked polymeric nanoparticles improves antiproliferative activity and apoptosis induction in liver …

S Ganesan, VJ Upadhye, D Aulakh… - Journal of Applied …, 2024 - Wiley Online Library
Nanoparticle (NP) enabled approaches have been employed for chemotherapeutic
administration due to their capacity to regulate drug release and reduce side effects …

Hybridization of tumor homing and mitochondria-targeting peptide domains to design novel dual-imaging self-assembled peptide nanoparticles for theranostic …

SFA Rizvi, S Shahid, S Mu, H Zhang - Drug Delivery and Translational …, 2022 - Springer
A novel hybridized dual-targeting peptide-based nanoprobe was successfully designed by
using the cyclic heptapeptide. This peptide has Arg-Gly-Asp-Lys-Leu-Ala-Lys sequence, in …