Fingolimod suppressed the chronic unpredictable mild stress-induced depressive-like behaviors via affecting microglial and NLRP3 inflammasome activation
Y Guo, X Gan, H Zhou, H Zhou, S Pu, X Long, C Ren… - Life Sciences, 2020 - Elsevier
Depression is a common aspect of the modern lifestyle, and most patients are recalcitrant to
the current antidepressants. Fingolimod (FTY720), a sphingosine analogue approved for the …
the current antidepressants. Fingolimod (FTY720), a sphingosine analogue approved for the …
[HTML][HTML] Fuxin Granules ameliorate diabetic nephropathy in db/db mice through TGF-β1/Smad and VEGF/VEGFR2 signaling pathways
W Zheng, C Qian, F Xu, P Cheng, C Yang, X Li… - Biomedicine & …, 2021 - Elsevier
Diabetic nephropathy (DN) is a common disease, and patients often do not have satisfactory
treatments. We investigated therapeutic effects of Fuxin Granules (FX) on DN and potential …
treatments. We investigated therapeutic effects of Fuxin Granules (FX) on DN and potential …
Persimmon leaf extract alleviates chronic social defeat stress-induced depressive-like behaviors by preventing dendritic spine loss via inhibition of serotonin reuptake …
Abstract Background Fresh or dried Persimmon leaves (Diospyros kaki Thunb.) exhibit
preventive effects on cardiovascular and cerebrovascular diseases. However, their …
preventive effects on cardiovascular and cerebrovascular diseases. However, their …
Medicinal plants and plant-based traditional medicine: Alternative treatments for depression and their potential mechanisms of action
J Remali, WM Aizat - Heliyon, 2024 - cell.com
Background Clinical depression is a serious public health issue that affects 4.7% of the
world's population and can lead to suicide tendencies. Although drug medications are …
world's population and can lead to suicide tendencies. Although drug medications are …
[HTML][HTML] Systemic pharmacological verification of Salvia miltiorrhiza-Ginseng Chinese herb pair in inhibiting spontaneous breast cancer metastasis
H Han, C Qian, G Zong, H Liu, F Wang, R Tao… - Biomedicine & …, 2022 - Elsevier
Breast cancer is the most commonly diagnosed cancer in the world, and metastasis is often
the main cause of death in breast cancer patients. Salvia miltiorrhiza-Ginseng (SG) herb pair …
the main cause of death in breast cancer patients. Salvia miltiorrhiza-Ginseng (SG) herb pair …
An integrative pharmacology-based pattern to uncover the pharmacological mechanism of ginsenoside H dripping pills in the treatment of depression
L Zhao, R Guo, N Cao, Y Lin, W Yang, S Pei… - Frontiers in …, 2021 - frontiersin.org
Objectives: To evaluate the pharmacodynamical effects and pharmacological mechanism of
Ginsenoside H dripping pills (GH) in chronic unpredictable mild stress (CUMS) model rats …
Ginsenoside H dripping pills (GH) in chronic unpredictable mild stress (CUMS) model rats …
Based on Systematic Pharmacology: Molecular Mechanism of Siwei Jianbu Decoction in Preventing Oxaliplatin‐Induced Peripheral Neuropathy
P Zhang, Y Lu, C Yang, Q Zhang, Y Qian… - Neural …, 2020 - Wiley Online Library
Chemotherapy‐induced peripheral neuropathy (CIPN) is a dose‐limiting side effect caused
by chemotherapy drugs, and its existence seriously affects the quality of life of patients. We …
by chemotherapy drugs, and its existence seriously affects the quality of life of patients. We …