Isothermal titration calorimetry (ITC) has become the gold standard for studying molecular
interactions in solution. Although it is increasingly being used in the soft matter and synthetic …

Isothermal Titration Calorimetry (ITC) elucidates the thermodynamic profile (ΔH, ΔS, ΔG, Ka,
and stoichiometry) of binding and dissociation reactions in solution. While ITC has primarily …

Abstract Enterovirus 71 (EV71) poses serious threats to human health, particularly in
Southeast Asia, and no drugs or vaccines are available. Previous work identified the stem …

The comprehension of molecular recognition phenomena demands the understanding of
the energetic and kinetic processes involved. General equations valid for the …

The ability to mimic the activity of natural enzymes using supramolecular constructs (artificial
enzymes) is a vibrant scientific research field. Herein, we demonstrate that cucurbit [7] uril …

Aptamers are nucleic acids that bind to a target molecule with high affinity and specificity,
which are selected from systematic evolution of ligands by exponential enrichment (SELEX) …

The last 5 years have seen a series of advances in the application of isothermal titration
microcalorimetry (ITC) and interpretation of ITC data. ITC has played an invaluable role in …

Natural pigments are bioactive compounds that can present health-promoting bioactivities in
the human body. Due to their strong coloring properties, these compounds have been …

Structure–activity relationships (SARs) and structure–property relationships (SPRs) have
been considered the most important factors during the drug optimization process. For …

Calorimetry is a classical biophysical method that by definition measures heat. In isothermal
titration calorimetry (ITC), the heat is the result of titrating interacting components together …