Nitrogen metabolism is an important physiological process that affects the survival and
virulence of Mycobacterium tuberculosis. M. tuberculosis's utilization of nitrogen in the …

Computational algorithms and tools have retrenched the drug discovery and development
timeline. The applicability of computational approaches has gained immense relevance …

Abstract l-Asparaginase is a therapeutically and industrially-competent enzyme, acting
predominantly as an anti-neoplastic and anti-cancerous agent. The existing formulations of …

Mycobacterium tuberculosis (M. tb), the causative pathogen of tuberculosis (TB) remains the
leading cause of death from single infectious agent. Furthermore, its evolution to multi-drug …

The emergence of multiple drug‐resistant “super gonorrhoea” complicates the management
and treatment of Neisseria gonorrhoeae infections due to the progressive accumulation of …

l-asparaginase is an enzyme catalyzing the hydrolysis of l-asparagine into l-aspartate and
ammonia, which is of great therapeutic importance in tumor treatment. However …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) infection, is a serious health
hazard, characterized by tuberculous granuloma formation, which may facilitate bacterial …

According to the latest World Health Organization (WHO) report, an estimated 10.6 million
people were diagnosed with tuberculosis (TB) in 2022, and 1.30 million died. A major …

Tuberculosis (TB) is a major issue in global health and affects millions of people each year.
Multidrug-resistant tuberculosis (MDR-TB) annually causes many deaths worldwide …

The emergence of drug-resistant Mycobacterium tuberculosis (Mtb) stains has escalated the
need for developing more efficient drugs and therapeutic strategies against tuberculosis …