Neoadjuvant therapy for pancreatic cancer

J Gugenheim, A Crovetto, N Petrucciani - Updates in surgery, 2022 - Springer
Multimodal treatment including surgery and chemotherapy is considered the gold standard
treatment of pancreatic cancer by most guidelines. Neoadjuvant therapy (NAT) has been …

[HTML][HTML] FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with …

JR Platt, OM Todd, P Hall, Z Craig, A Quyn, M Seymour… - ESMO open, 2023 - Elsevier
Treating older adults with cancer is increasingly important in modern oncology practice.
However, we currently lack the high-quality evidence needed to guide optimal management …

Gemcitabine/nab-paclitaxel versus FOLFIRINOX in locally advanced pancreatic cancer: A European multicenter study

N Williet, A Petrillo, G Roth, M Ghidini, M Petrova… - Cancers, 2021 - mdpi.com
Simple Summary Gemcitabine/nab-paclitaxel (GN) and FOLFIRINOX (FFX) are two standard
first-line therapies for metastatic pancreatic cancer (PC) but have rarely been compared …

Multicenter Prospective Cohort Study of Neoadjuvant Chemotherapy for Borderline Resectable Pancreatic Cancer (YPB-001)

H Matsui, T Ioka, T Takahashi, T Kawaoka, Y Maeda… - Pancreas, 2024 - journals.lww.com
Objectives The present multicenter prospective observational study investigated the
effectiveness and safety of neoadjuvant chemotherapy (NAC) for patients with borderline …

[HTML][HTML] Surgical management for elderly patients with pancreatic cancer

SW Kim - Annals of Surgical Treatment and Research, 2023 - synapse.koreamed.org
Pancreatic cancer, one of the diseases of the elderly, has dismal prognosis, demanding
major surgery with high risk and life quality problems, especially in the elderly. Therefore …

Validating biologic age in selecting elderly patients with pancreatic cancer for surgical resection

AJ Scholer, R Marcus… - Journal of surgical …, 2023 - Wiley Online Library
Abstract Background and Objectives Selecting frail elderly patients with pancreatic cancer
(PC) for pancreas resection using biologic age has not been elucidated. This study …

Determination of arterial invasion in pancreatic ductal adenocarcinoma: what is the best diagnostic criterion on CT?

Y Noda, N Mizuno, N Kawai, T Ando, M Kawaguchi… - European …, 2023 - Springer
Objectives To investigate the diagnostic performance and interobserver variability in the
determination of arterial invasion in pancreatic ductal adenocarcinoma (PDAC) and …

Perioperative outcomes in an age-adapted analysis of the German StuDoQ| Pancreas registry for PDAC

T Tschaidse, FO Hofmann, B Renz, M Hungbauer… - BMC surgery, 2025 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) typically occurs in an older patient
population. Yet, early-onset pancreatic cancer (EOPC) has one of the fastest growing …