Pharmacological and pharmaceutical profile of valsartan: a review

N Siddiqui, A Husain, L Chaudhry, MS Alam… - Journal of Applied …, 2011 - japsonline.com
Angiotensin II Receptor type 1 antagonists have been widely used in treatment of diseases
like hypertension, heart failure, myocardial infarction and diabetic nephropathy. Their …

Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites

B Schmidt, B Schieffer - Journal of medicinal chemistry, 2003 - ACS Publications
The renin angiotensin system (RAS) is one of the most powerful regulators of blood pressure
and volume homeostasis in mammals. Its effector peptide angiotensin II (ANG II) is cleaved …

Simultaneous determination of 6 beta-blockers, 3 calcium-channel antagonists, 4 angiotensin-II antagonists and 1 antiarrhytmic drug in post-mortem whole blood by …

L Kristoffersen, EL Øiestad, MS Opdal, M Krogh… - … of Chromatography B, 2007 - Elsevier
A method for the simultaneous determination of the beta-blockers atenolol, sotalol,
metoprolol, bisoprolol, propranolol and carvedilol, the calcium-channel antagonists …

Rapid determination of valsartan in human plasma by protein precipitation and high-performance liquid chromatography

J Macek, J Klima, P Ptáček - Journal of Chromatography B, 2006 - Elsevier
A high-performance liquid chromatographic (HPLC) method for the determination of
valsartan in human plasma is reported. The assay is based on protein precipitation with …

A liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of valsartan and hydrochlorothiazide in human plasma

H Li, Y Wang, Y Jiang, Y Tang, J Wang, L Zhao… - … of Chromatography B, 2007 - Elsevier
A rapid and sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS)
method was developed and validated for simultaneous quantification of valsartan and …

Development of the “Inje Cocktail” for High‐throughput Evaluation of Five Human Cytochrome P450 Isoforms in vivo

JY Ryu, IS Song, YE Sunwoo, JH Shon… - Clinical …, 2007 - Wiley Online Library
To develop and validate an in vivo cocktail method for high‐throughput phenotyping of
CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A, 12 healthy subjects received five …

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Valsartan and Amlodipine in Capsule Formulation.

SS Chitlange, K Bagri… - Asian Journal of Research …, 2008 - indianjournals.com
Present work describes a precise, accurate and reproducible Reverse phase High
Performance Liquid Chromatographic (RP-HPLC) method for simultaneous estimation of …

Synthesis of molecularly imprinted polymer as a nanosorbent for dispersive magnetic micro solid-phase extraction and determination of valsartan in biological …

N Azizi-Khereshki, HZ Mousavi, MG Dogaheh… - … Acta Part A: Molecular …, 2023 - Elsevier
A magnetic molecularly imprinted polymer (MIP) was synthesized by precipitation
polymerization utilizing Fe 3 O 4@ SiO 2-MPS as a magnetic core, itaconic acid as a …

Simultaneous determination of fixed dose combination of nebivolol and valsartan in human plasma by liquid chromatographic-tandem mass spectrometry and its …

PS Selvan, KV Gowda, U Mandal… - … of Chromatography B, 2007 - Elsevier
A rapid, sensitive and accurate liquid chromatographic-tandem mass spectrometry method
is described for the simultaneous determination of nebivolol and valsartan in human plasma …

Losartan: comprehensive profile

ARA Al-Majed, E Assiri, NY Khalil… - Profiles of Drug …, 2015 - Elsevier
Losartan (Cozaar™) is an angiotensin II receptor antagonist with antihypertensive activity. It
is used in the management of hypertension and heart failure. Nomenclature, formulae …