Abstract Caspase‐3, a cysteine‐aspartic acid protease, has recently attracted much
attention because of its incredible roles in tissue differentiation, regeneration, and neural …

Apoptosis, a form of programmed cell death, is responsible for eliminating damaged or
unnecessary cells in multicellular organisms. Various types of intracellular stress trigger …

The innate immune system in vertebrates and invertebrates relies on conserved receptors
and ligands, and pathways that can rapidly initiate the host response against microbial …

Simple Summary The Inhibitor of Apoptosis (IAP) family of proteins has emerged as a
potential pharmacological target in cancer. Abnormal expression of IAPs can lead to …

The innate immune system plays a pivotal role in the first line of host defense against
infections and is equipped with patterns recognition receptors (PRRs) that recognize …

Inhibitor of apoptosis (IAP) family comprises a group of endogenous proteins that function as
main regulators of caspase activity and cell death. They are considered the main culprits in …

Autoimmune diseases are chronic immune diseases characterized by dysregulation of
immune system, which ultimately results in a disruption in self-antigen tolerance. Cumulative …

Innate immunity comprises several inflammation-related modulatory pathways which receive
signals from an array of membrane-bound and cytoplasmic pattern recognition receptors …

Abstract Inhibitors of Apoptosis (IAPs) are a family of proteins with various biological
functions including regulation of innate immunity and inflammation, cell proliferation, cell …

Viral infection triggers host pattern recognition receptors (PRRs) to recognize pathogen-
associated molecular patterns or danger-associated molecular patterns to initiate antiviral …