Planarians are a group of flatworms. Some planarian species have remarkable regenerative
abilities, which involve abundant pluripotent adult stem cells. This makes these worms a …

This review explores the historical and current state of our knowledge about urodele limb
regeneration. Topics discussed are (1) blastema formation by the proteolytic histolysis of …

The freshwater polyp Hydra provides a potent model system for investigating the conditions
that promote wound healing, reactivation of a developmental process and, ultimately …

Polyps of the cnidarian Hydra maintain their adult anatomy through two developmental
organizers, the head organizer located apically and the foot organizer basally. The head …

Here we discuss the developmental and homeostatic conditions necessary for Hydra
regeneration. Hydra is characterized by populations of adult stem cells paused in the G2 …

Colonial ascidians are the only chordates able to undergo whole body regeneration (WBR),
during which entire new bodies can be regenerated from small fragments of blood vessels …

Why some animals can regenerate and others not has fascinated biologists since the first
examples of regeneration were reported. Although many animal phyla include species with …

Achieving regeneration in humans has been a long-standing goal of many researchers.
Whereas amphibians like the axolotl (Ambystoma mexicanum) are capable of regenerating …

Background The canonical Wnt inhibitor Dickkopf-1 (Dkk-1) has the capacity to modulate
homeostasis between canonical and non-canonical Wnt pathways and also signal …

The cnidarian Hydra is a classical model of whole-body regeneration. Historically, Hydra
apical regeneration has received more attention than its basal counterpart, most studies …