International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma

AW Lee, WT Ng, JJ Pan, SS Poh, YC Ahn… - Radiotherapy and …, 2018 - Elsevier
Purpose Target delineation in nasopharyngeal carcinoma (NPC) often proves challenging
because of the notoriously narrow therapeutic margin. High doses are needed to achieve …

Long‐term outcomes after reirradiation in nasopharyngeal carcinoma with intensity‐modulated radiotherapy: a meta‐analysis

YH Leong, YY Soon, KM Lee, LC Wong… - Head & …, 2018 - Wiley Online Library
Background The purpose of this clinical review was to summate the published data for the
long‐term outcomes of reirradiation with intensity‐modulated radiotherapy (IMRT) for locally …

Emerging treatment options for nasopharyngeal carcinoma

L Zhang, QY Chen, H Liu, LQ Tang… - … design, development and …, 2013 - Taylor & Francis
Nasopharyngeal carcinoma is endemic in Asia and is etiologically associated with Epstein–
Barr virus. Radiotherapy is the primary treatment modality. The role of systemic therapy has …

Update report of nasopharyngeal carcinoma treated with reduced-volume intensity-modulated radiation therapy and hypothesis of the optimal margin

S Lin, J Pan, LU Han, Q Guo, C Hu, J Zong… - Radiotherapy and …, 2014 - Elsevier
Background and purpose To establish the minimally required margins in different directions
measured from GTV in the definitive treatment of nasopharyngeal carcinoma (NPC) using …

Salvage treatment using carbon ion radiation in patients with locoregionally recurrent nasopharyngeal carcinoma: Initial results

J Hu, C Bao, J Gao, X Guan, W Hu, J Yang, C Hu… - Cancer, 2018 - Wiley Online Library
BACKGROUND Reirradiation for locoregionally recurrent nasopharyngeal carcinoma (NPC)
after a definitive dose of radiotherapy (RT) is challenging and usually associated with severe …

[HTML][HTML] Chemoradiotherapy versus radiotherapy alone in stage II nasopharyngeal carcinoma: a systemic review and meta-analysis of 2138 patients

C Xu, LH Zhang, YP Chen, X Liu, GQ Zhou… - Journal of …, 2017 - ncbi.nlm.nih.gov
Background: To explore the value of chemoradiotherapy (CRT) in stage II nasopharyngeal
carcinoma (NPC) compared to radiotherapy (RT) alone which includes two-dimensional …

Salvage intensity-modulated radiation therapy (IMRT) for locally recurrent nasopharyngeal cancer after definitive IMRT: a novel scenario of the modern era

L Kong, L Wang, C Shen, C Hu, L Wang, JJ Lu - Scientific reports, 2016 - nature.com
Locally recurrent nasopharyngeal carcinoma (rNPC) after definitive IMRT occurs in 10% of
all cases and represents a distinct clinical entity that has been selectively enriched by radio …

Neoadjuvant chemotherapy followed by concurrent chemoradiation for locoregionally advanced nasopharyngeal carcinoma: interim results from 2 prospective phase …

L Kong, C Hu, X Niu, Y Zhang, Y Guo, IWK Tham… - Cancer, 2013 - Wiley Online Library
BACKGROUND The authors studied the efficacy of neoadjuvant chemotherapy, consisting
of a taxane, cisplatin, and 5‐fluorouracil (5‐FU)(the TPF regimen) followed by concurrent …

Intensity-modulated radiotherapy with simultaneous integrated boost for locoregionally advanced nasopharyngeal carcinoma

J Yi, X Huang, L Gao, J Luo, S Zhang, K Wang, Y Qu… - Radiation …, 2014 - Springer
Objective To compare the treatment outcomes of intensity-modulated radiotherapy with
simultaneous integrated boost (IMRT-SIB) alone to concurrent chemoradiotherapy (CCRT) …

A randomized clinical trial comparing prophylactic upper versus whole‐neck irradiation in the treatment of patients with node‐negative nasopharyngeal carcinoma

JG Li, X Yuan, LL Zhang, YQ Tang, L Liu, XD Chen… - Cancer, 2013 - Wiley Online Library
BACKGROUND This study sought to compare the clinical outcomes of upper versus whole‐
neck prophylactic irradiation in the treatment of patients with node‐negative nasopharyngeal …