Structural and functional imaging of brains
Analyzing the complex structures and functions of brain is the key issue to understanding the
physiological and pathological processes. Although neuronal morphology and local …
physiological and pathological processes. Although neuronal morphology and local …
Can one concurrently record electrical spikes from every neuron in a mammalian brain?
The classic approach to measure the spiking response of neurons involves the use of metal
electrodes to record extracellular potentials. Starting over 60 years ago with a single …
electrodes to record extracellular potentials. Starting over 60 years ago with a single …
[HTML][HTML] Virtual histology of an entire mouse brain from formalin fixation to paraffin embedding. Part 1: Data acquisition, anatomical feature segmentation, tracking …
Background: Micrometer-resolution neuroimaging with gold-standard conventional histology
requires tissue fixation and embedding. The exchange of solvents for the creation of …
requires tissue fixation and embedding. The exchange of solvents for the creation of …
Noninvasive Three-Dimensional In Situ and In Vivo Characterization of Bioprinted Hydrogel Scaffolds Using the X-ray Propagation-Based Imaging Technique
Hydrogel-based three-dimensional (3D) bioprinting has been illustrated as promising to
fabricate tissue scaffolds for regenerative medicine. Notably, bioprinting of hydrated and soft …
fabricate tissue scaffolds for regenerative medicine. Notably, bioprinting of hydrated and soft …
A highly accurate quantum optimization algorithm for CT image reconstruction based on sinogram patterns
K Jun - Scientific Reports, 2023 - nature.com
Computed tomography (CT) has been developed as a nondestructive technique for
observing minute internal images in samples. It has been difficult to obtain photorealistic …
observing minute internal images in samples. It has been difficult to obtain photorealistic …
Multidisciplinary and multiscale nanoscience research roadmap based on large scientific facilities
Y Zeng, S Zhang, Y Guo, Y Cong, X Ding, P Li… - Science China …, 2024 - Springer
With the advancement of modern science and technology, large scientific facilities are
increasingly oriented toward demand and application, and can be used for basic research …
increasingly oriented toward demand and application, and can be used for basic research …
Transcriptional characterization of the glial response due to chronic neural implantation of flexible microprobes
Long term implantation of (micro-) probes into neural tissue causes unique and disruptive
responses. In this study, we investigate the transcriptional trajectory of glial cells responding …
responses. In this study, we investigate the transcriptional trajectory of glial cells responding …
Chronically Implanted Microelectrodes Cause c-fos Expression Along Their Trajectory
P Pflüger, RC Pinnell, N Martini… - Frontiers in …, 2020 - frontiersin.org
When designing electrodes and probes for brain–machine interfaces, one of the challenges
faced involves minimizing the brain-tissue response, which would otherwise create an …
faced involves minimizing the brain-tissue response, which would otherwise create an …
On the cusp of x-ray tomographic mapping of the human brain and its 1011 cells
B Müller - Developments in X-Ray Tomography XV, 2024 - spiedigitallibrary.org
The human brain contains 86 billion cells, but so far only a part could be visualized. The task
corresponds to the acquisition and treatment of a petabyte-size dataset–analogous to …
corresponds to the acquisition and treatment of a petabyte-size dataset–analogous to …
Intracortical probe arrays with silicon backbone and microelectrodes on thin polyimide wings enable long-term stable recordings in vivo
A Kilias, YT Lee, UP Froriep, C Sielaff… - Journal of Neural …, 2021 - iopscience.iop.org
Objective. Recording and stimulating neuronal activity across different brain regions
requires interfacing at multiple sites using dedicated tools while tissue reactions at the …
requires interfacing at multiple sites using dedicated tools while tissue reactions at the …