Oral squamous cell carcinoma: Key clinical questions, biomarker discovery, and the role of proteomics

UU Malik, S Zarina, SR Pennington - Archives of oral biology, 2016 - Elsevier
Background The molecular and cellular mechanisms underlying the pathogenesis of oral
squamous cell carcinoma (OSCC) are relatively poorly understood and remain a subject of …

Head and neck cancer: proteomic advances and biomarker achievements

TMB Rezende, MS Freire, OL Franco - Cancer, 2010 - Wiley Online Library
Tumors of the head and neck comprise an important neoplasia group, the incidence of
which is increasing in many parts of the world. Recent advances in diagnostic and …

Association of the actin-binding protein transgelin with lymph node metastasis in human colorectal cancer

Y Lin, PJ Buckhaults, JR Lee, H Xiong, C Farrell… - Neoplasia, 2009 - Elsevier
Metastatic dissemination of primary tumors is responsible for 90% of colorectal cancer
(CRC) deaths. The presence of positive lymph nodes, which separates stage I/II from stage …

Nomograms forecasting long‐term overall and cancer‐specific survival of patients with oral squamous cell carcinoma

F Wang, H Zhang, J Wen, J Zhou, Y Liu… - Cancer …, 2018 - Wiley Online Library
Our aim was to establish a “nomogram” model to forecast the overall survival (OS) and
cancer‐specific survival (CSS) of oral squamous cell carcinoma (OSCC) patients. The …

Nomograms for predicting long‐term overall survival and cancer‐specific survival in lip squamous cell carcinoma: a population‐based study

CY Hu, ZY Pan, J Yang, XH Chu, J Zhang… - Cancer …, 2019 - Wiley Online Library
Background The goal of this study was to establish and validate two nomograms for
predicting the long‐term overall survival (OS) and cancer‐specific survival (CSS) in lip …

[HTML][HTML] Furosemide-induced systemic dehydration alters the proteome of rabbit vocal folds

NC do Nascimento, AP Dos Santos, R Mohallem… - Journal of …, 2022 - Elsevier
Whole-body dehydration (ie, systemic dehydration) leads to vocal fold tissue dehydration.
Furosemide, a common diuretic prescribed to treat hypertension and edema-associated …

Cytokeratin-8 in anaplastic thyroid carcinoma: More than a simple structural cytoskeletal protein

D Guo, Q Xu, S Pabla, J Koomen, P Biddinger… - International journal of …, 2018 - mdpi.com
Anaplastic thyroid carcinoma (ATC) is almost universally fatal. Elevated keratin-8 (KRT8)
protein expression is an established diagnostic cancer biomarker in several epithelial …

Larynx proteomics after jellyfish collagen IL: Increased ECM/collagen and suppressed inflammation

AJ Bowen, DC Ekbom, D Hunter, S Voss… - Laryngoscope …, 2022 - Wiley Online Library
Abstract Objectives/Hypothesis Compare proteomic profiles of rabbit vocal folds (VFs)
injected with micronized cross‐linked jellyfish collagen “collagen Type 0”(MX‐JC) against …

Retinoblastoma and p53 protein expression in pre-malignant oral lesions and oral squamous cell carcinoma

MG De Oliveira, LMP Ramalho… - Molecular …, 2012 - spandidos-publications.com
The retinoblastoma (Rb) and p53 genes play a fundamental role in cell cycle mechanisms,
and their deregulation is related to many steps of oral cancer carcinogenesis. This study was …

[HTML][HTML] Proteomic identification of alpha-2-HS-glycoprotein as a plasma biomarker of hypopharyngeal squamous cell carcinoma

WD Tian, JZ Li, SW Hu, XW Peng, G Li… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Hypopharyngeal squamous cell carcinoma (HSCC) has very poor prognosis compared with
other head and neck squamous cell carcinomas. Late-stage diagnosis of HSCC increases …