Occurrence, structure, and evolution of nitric oxide synthase–like proteins in the plant kingdom

S Jeandroz, D Wipf, DJ Stuehr, L Lamattina… - Science …, 2016 - science.org
Nitric oxide (NO) signaling regulates various physiological processes in both animals and
plants. In animals, NO synthesis is mainly catalyzed by NO synthase (NOS) enzymes …

Zinc coordination sphere in biochemical zinc sites

DS Auld - Zinc biochemistry, physiology, and homeostasis: recent …, 2001 - Springer
Zinc is known to be indispensable to growth and development and transmission of the
genetic message. It does this through a remarkable mosaic of zinc binding motifs that …

Nitric oxide synthase in plants: where do we stand?

J Santolini, F André, S Jeandroz, D Wendehenne - Nitric Oxide, 2017 - Elsevier
Over the past twenty years, nitric oxide (NO) has emerged as an important player in various
plant physiological processes. Although many advances in the understanding of NO …

Protein interactions with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide

BC Kone, T Kuncewicz, W Zhang… - American Journal of …, 2003 - journals.physiology.org
Nitric oxide (NO) is a potent cell-signaling, effector, and vasodilator molecule that plays
important roles in diverse biological effects in the kidney, vasculature, and many other …

Structure–function studies on nitric oxide synthases

H Li, TL Poulos - Journal of inorganic biochemistry, 2005 - Elsevier
Nitric oxide synthase (NOS) catalyzes the oxidation of one l-arginine guanidinium N atom to
nitric oxide (NO). NOS consists of a heme domain linked to a flavin mononucleotide …

[PDF][PDF] Nitric oxide synthases: domain structure and alignment in enzyme function and control

DK Ghosh, JC Salerno - Front Biosci, 2003 - academia.edu
[Frontiers in Bioscience 8, d193-209, January 1, 2003] 193 NITRIC OXIDE SYNTHASES:
DOMAIN STRUCTURE AND ALIGNMENT IN ENZYME FUNC Page 1 [Frontiers in …

Distinct dimer interaction and regulation in nitric-oxide synthase types I, II, and III

K Panda, RJ Rosenfeld, S Ghosh, AL Meade… - Journal of Biological …, 2002 - ASBMB
Homodimer formation activates all nitric-oxide synthases (NOSs). It involves the interaction
between two oxygenase domains (NOSoxy) that each bind heme and (6R) …

Structure of a Nitric Oxide Synthase Heme Protein from Bacillus subtilis,

K Pant, AM Bilwes, S Adak, DJ Stuehr, BR Crane - Biochemistry, 2002 - ACS Publications
Eukaryotic nitric oxide synthases (NOSs) produce nitric oxide to mediate intercellular
signaling and protect against pathogens. Recently, proteins homologous to mammalian …

Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans

S Adak, AM Bilwes, K Panda… - Proceedings of the …, 2002 - National Acad Sciences
We cloned, expressed, and characterized a hemeprotein from Deinococcus radiodurans (D.
radiodurans NO synthase, deiNOS) whose sequence is 34% identical to the oxygenase …

Role of bound zinc in dimer stabilization but not enzyme activity of neuronal nitric-oxide synthase

B Hemmens, W Goessler, K Schmidt… - Journal of Biological …, 2000 - ASBMB
Nitric-oxide synthases (NOS) are homodimeric proteins and can form an intersubunit Zn (4S)
cluster. We have measured zinc bound to NOS purified from pig brain (0.6 mol/mol of NOS) …