It is now appreciated that emerging therapeutic strategies for recovery must include the
cerebral vasculature and that induction of angiogenesis will stimulate endogenous recovery …

Background Vascular endothelial growth factor (VEGF) is a naturally occurring glycoprotein
in the body that acts as a growth factor for endothelial cells. It regulates angiogenesis …

Importance Understanding the natural history of visual outcome in branch retinal vein
occlusion (BRVO) is fundamental to its management. Objective To investigate the natural …

Figures released in 2013 by the International Diabetes Federation (IDF) state that over 382
million individuals worldwide are affected by diabetes mellitus (DM). 1 The global …

Subretinal neovascularization and pathologic ocular angiogenesis are common causes of
progressive, irreversible impairment of central vision, and dramatically affect quality of life …

Ranibizumab (Lucentis®), an inhibitor of all vascular endothelial growth factor (VEGF) A
isoforms, is approved for the intravitreal treatment of neovascular age-related macular …

Purpose.: Rho kinase (ROCK) is associated with VEGF-driven angiogenesis, as well as with
inflammation and fibrosis. Therefore, the effect of AMA0428, a novel ROCK inhibitor, was …

Aim This study compared systemic and intraocular concentrations of erythropoietin (EPO)
and vascular endothelial growth factor (VEGF) in patients with type 2 diabetes (T2D) and …

Choroidal neovascularization (CNV) is a hallmark of wet age-related macular degeneration,
which severely impairs central vision. Studies have shown that endothelial-mesenchymal …

Introduction: Anti-VEGF therapy improved the quality of life for millions of patients suffering
from wet age-related macular degeneration (wet-AMD); unfortunately, this therapy involves …