[PDF][PDF] Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases
Neuregulins (NRGs) comprise a large family of growth factors that stimulate ERBB receptor
tyrosine kinases. NRGs and their receptors, ERBBs, have been identified as susceptibility …
tyrosine kinases. NRGs and their receptors, ERBBs, have been identified as susceptibility …
Neuregulin-1 and schizophrenia in the genome-wide association study era
Clinical and pre-clinical evidence has implicated neuregulin 1 (NRG1) as a critical
component in the pathophysiology of schizophrenia. However, the arrival of the genome …
component in the pathophysiology of schizophrenia. However, the arrival of the genome …
Consensus paper of the WFSBP Task Force on Biological Markers: Criteria for biomarkers and endophenotypes of schizophrenia part II: Cognition, neuroimaging and …
Objectives: Schizophrenia is a group of severe psychiatric disorders with high heritability but
only low odds ratios of risk genes. Despite progress in the identification of …
only low odds ratios of risk genes. Despite progress in the identification of …
Schizophrenia-associated HapICE haplotype is associated with increased NRG1 type III expression and high nucleotide diversity
CS Weickert, Y Tiwari, PR Schofield, BJ Mowry… - Translational …, 2012 - nature.com
Excitement and controversy have followed neuregulin (NRG1) since its discovery as a
putative schizophrenia susceptibility gene; however, the mechanism of action of the …
putative schizophrenia susceptibility gene; however, the mechanism of action of the …
Insights to the schizophrenia continuum: A systematic review of saccadic eye movements in schizotypy and biological relatives of schizophrenia patients
Abstract Myles, JB, S. Rossell, A. Phillipou, Thomas, E and C. Gurvich. A systematic review
of saccadic eye movements across the schizophrenia continuum: Characterisation …
of saccadic eye movements across the schizophrenia continuum: Characterisation …
Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study
Eye movement deviations, particularly deficits of initial sensorimotor processing and
sustained pursuit maintenance, and antisaccade inhibition errors, are established …
sustained pursuit maintenance, and antisaccade inhibition errors, are established …
[PDF][PDF] Current challenges and possible future developments in personalized psychiatry with an emphasis on psychotic disorders
A Levchenko, T Nurgaliev, A Kanapin, A Samsonova… - Heliyon, 2020 - cell.com
A personalized medicine approach seems to be particularly applicable to psychiatry. Indeed,
considering mental illness as deregulation, unique to each patient, of molecular pathways …
considering mental illness as deregulation, unique to each patient, of molecular pathways …
Association study of neuregulin-1 gene polymorphisms in a North Indian schizophrenia sample
BACKGROUND: Neuregulin-1 (NRG1) gene polymorphisms have been proposed as risk
factors for several common disorders. Associations with cognitive variation have also been …
factors for several common disorders. Associations with cognitive variation have also been …
The influence of schizophrenia-related neuregulin-1 polymorphisms on sensorimotor gating in healthy males
P Roussos, SG Giakoumaki, E Adamaki, P Bitsios - Biological psychiatry, 2011 - Elsevier
BACKGROUND:: Neuregulin-1 (NRG1) variations have been shown to modulate
schizophrenia candidate endophenotypes related to brain structure and function. The …
schizophrenia candidate endophenotypes related to brain structure and function. The …
[HTML][HTML] BACE1-dependent neuregulin-1 signaling: an implication for schizophrenia
Schizophrenia is a chronic psychiatric disorder with a lifetime prevalence of about 1% in the
general population. Recent studies have shown that Neuregulin-1 (Nrg1) is a candidate …
general population. Recent studies have shown that Neuregulin-1 (Nrg1) is a candidate …