Collagen—emerging collagen based therapies hit the patient

EA Abou Neel, L Bozec, JC Knowles, O Syed… - Advanced drug delivery …, 2013 - Elsevier
The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …

Restoration of sensorimotor functions after spinal cord injury

V Dietz, K Fouad - Brain, 2014 - academic.oup.com
The purpose of this review is to discuss the achievements and perspectives regarding
rehabilitation of sensorimotor functions after spinal cord injury. In the first part we discuss …

Drug delivery, cell-based therapies, and tissue engineering approaches for spinal cord injury

S Kabu, Y Gao, BK Kwon, V Labhasetwar - Journal of Controlled Release, 2015 - Elsevier
Spinal cord injury (SCI) results in devastating neurological and pathological consequences,
causing major dysfunction to the motor, sensory, and autonomic systems. The primary …

Mesenchymal stem cells improve locomotor recovery in traumatic spinal cord injury: systematic review with meta-analyses of rat models

RS Oliveri, S Bello, F Biering-Sørensen - Neurobiology of disease, 2014 - Elsevier
Traumatic spinal cord injury (SCI) is a devastating event with huge personal and societal
costs. A limited number of treatments exist to ameliorate the progressive secondary damage …

Human spinal oligodendrogenic neural progenitor cells promote functional recovery after spinal cord injury by axonal remyelination and tissue sparing

N Nagoshi, M Khazaei, JE Ahlfors… - Stem cells …, 2018 - academic.oup.com
Cell transplantation therapy utilizing neural precursor cells (NPCs) is a conceptually
attractive strategy for traumatic spinal cord injury (SCI) to replace lost cells, remyelinate …

A novel porcine model of traumatic thoracic spinal cord injury

JHT Lee, CF Jones, EB Okon, L Anderson… - Journal of …, 2013 - liebertpub.com
Spinal cord injury (SCI) researchers have predominately utilized rodents and mice for in vivo
SCI modeling and experimentation. From these small animal models have come many …

Astaxanthin attenuates neuroinflammation contributed to the neuropathic pain and motor dysfunction following compression spinal cord injury

S Fakhri, L Dargahi, F Abbaszadeh, M Jorjani - Brain research bulletin, 2018 - Elsevier
Spinal cord injury (SCI) is a debilitating condition in which inflammatory responses in the
secondary phase of injury leads to long lasting sensory-motor dysfunction. The medicinal …

iPSC-derived neural precursor cells: potential for cell transplantation therapy in spinal cord injury

N Nagoshi, H Okano - Cellular and Molecular Life Sciences, 2018 - Springer
A number of studies have demonstrated that transplantation of neural precursor cells (NPCs)
promotes functional recovery after spinal cord injury (SCI). However, the NPCs had been …

Development of the Graded Redefined Assessment of Strength, Sensibility and Prehension (GRASSP): reviewing measurement specific to the upper limb in …

S Kalsi-Ryan, A Curt, MC Verrier… - Journal of Neurosurgery …, 2012 - thejns.org
Object Primary outcome measures for the upper limb in trials concerning human spinal cord
injury (SCI) need to distinguish between functional and neurological changes and require …

Evaluation of spinal cord injury animal models

N Zhang, M Fang, H Chen, F Gou… - Neural regeneration …, 2014 - journals.lww.com
Because there is no curative treatment for spinal cord injury, establishing an ideal animal
model is important to identify injury mechanisms and develop therapies for individuals …