Catalytic hairpin assembly (CHA) with advantages of high efficiency, flexible design, and
mild reaction condition is considered a promising molecular amplifier. Modified working …

Abstract Development of food detection strategies provides chances for the determination of
contaminants in foodstuffs. Optical detection approaches which are based on light …

The detection of biomarkers is the future of non-invasive medical diagnosis and screening.
Discovery and identification of reliable disease specific volatile organic compounds is …

Circulating tumor DNA (ctDNA) detection has found widespread applications in tumor
diagnostics and treatment, where the key is to obtain accurate quantification of ctDNA …

As one of the two nucleic acids used by extant biochemistry, RNA is of great importance for
cellular function and development, and its expression can affect cell homeostasis. Therefore …

One major drawback to the traditional loop-mediated isothermal amplification (LAMP)
detection methods is the increased likelihood of detecting false-positive signals derived from …

Single nucleotide polymorphisms (SNPs), which seem to be vast differences in gene
sequences, are the primary cause of individual variability. Moreover, multiple devastating …

The emergence of the coronavirus 2019 (COVID-19) arose the need for rapid, accurate and
massive virus detection methods to control the spread of infectious diseases. In this work, a …

MicroRNAs (miRNAs) are responsible for post-transcriptional gene expression regulation
and they widely participate in different cell development processes. Dysregulation of …

Spherical nucleic acids (SNAs) are three-dimensional and polyvalent nanostructures with
highly oriented and densely arranged nucleic acids shell attached to the surface of …