Chronic intermittent hypoxia enhances glycinergic inhibition in nucleus tractus solitarius

S Jia, N Rybalchenko, K Kunwar… - Journal of …, 2022 - journals.physiology.org
Chronic intermittent hypoxia (CIH), an animal model of sleep apnea, has been shown to
alter the activity of second-order chemoreceptor neurons in the caudal nucleus of the solitary …

Selective breeding for physical inactivity produces cognitive deficits via altered hippocampal mitochondrial and synaptic function

NR Kerr, TJ Kelty, X Mao, TE Childs… - Frontiers in Aging …, 2023 - frontiersin.org
Physical inactivity is the 4th leading cause of death globally and has been shown to
significantly increase the risk for developing Alzheimer's Disease (AD). Recent work has …

Nucleus tractus solitarii is required for the development and maintenance of phrenic and sympathetic long-term facilitation after acute intermittent hypoxia

D Ostrowski, CM Heesch, DD Kline… - Frontiers in …, 2023 - frontiersin.org
Exposure to acute intermittent hypoxia (AIH) induces prolonged increases (long term
facilitation, LTF) in phrenic and sympathetic nerve activity (PhrNA, SNA) under basal …

Cardiovascular deconditioning increases GABA signaling in the nucleus tractus solitarii

L Lima-Silveira, EM Hasser… - Journal of …, 2022 - journals.physiology.org
The nucleus tractus solitarii (nTS) is the major integrative brainstem region for autonomic
modulation and processing of cardiovascular reflexes. GABA and glutamate are the main …

Oxytocin and corticotropin‐releasing hormone exaggerate nucleus tractus solitarii neuronal and synaptic activity following chronic intermittent hypoxia

P Gama de Barcellos Filho, HA Dantzler… - The Journal of …, 2024 - Wiley Online Library
Chronic intermittent hypoxia (CIH) in rodents mimics the hypoxia‐induced elevation of blood
pressure seen in individuals experiencing episodic breathing. The brainstem nucleus tractus …

Evaluating the Molecular Drivers of Physical Inactivity and Muscle Atrophy as Initiating Factors in Cognitive Impairment

NR Kerr - 2023 - search.proquest.com
Physical activity has played an essential role in the evolution of humans and the
development of the human brain. Therefore, it comes as no surprise that the modern-day …