Natural killer cell-based immunotherapy for acute myeloid leukemia

J Xu, T Niu - Journal of hematology & oncology, 2020 - Springer
Despite considerable progress has been achieved in the treatment of acute myeloid
leukemia over the past decades, relapse remains a major problem. Novel therapeutic …

Preclinical and clinical development of therapeutic antibodies targeting functions of CD47 in the tumor microenvironment

S Kaur, KV Cicalese, R Banerjee… - Antibody …, 2020 - academic.oup.com
ABSTRACT CD47 is a ubiquitously expressed cell surface glycoprotein that functions as a
signaling receptor for thrombospondin-1 and as the counter-receptor for signal regulatory …

Green-synthesized silver nanoparticles from peel extract of pumpkin as a potent radiosensitizer against triple-negative breast cancer (TNBC)

S Montazersaheb, A Eftekhari, A Shafaroodi… - Cancer …, 2024 - Springer
Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast
cancer. Radiation therapy (RT) is a modality for TNBC management. Radiosensitizers can …

Role of CD47 in tumor immunity: a potential target for combination therapy

J Huang, F Liu, C Li, X Liang, C Li, Y Liu, Z Yi… - Scientific Reports, 2022 - nature.com
CD47 performs a vital function in cancer therapy by binding to different SIRPα,
thrombospondin 1, and integrin. However, its role in tumor immunity and its correlation with …

Quercetin as a novel therapeutic approach for lymphoma

SR Soofiyani, K Hosseini… - Oxidative Medicine …, 2021 - Wiley Online Library
Lymphoma is a name for malignant diseases of the lymphatic system including Hodgkin's
lymphoma and non‐Hodgkin's lymphoma. Although several approaches are used for the …

Cord-blood natural killer cell-based immunotherapy for cancer

X Zhao, L Cai, Y Hu, H Wang - Frontiers in Immunology, 2020 - frontiersin.org
Natural killer (NK) cells are a predominant part of innate immune cells and play a crucial role
in anti-cancer immunity. NK cells can kill target cells nonspecifically, and their recognition of …

The role of KIR positive NK cells in diseases and its importance in clinical intervention

KD Asl, K Velaei, A Rafat, HT Nasrabadi… - International …, 2021 - Elsevier
Natural killer (NK) cells are essential for the elimination of the transformed and cancerous
cells. Killer cell immunoglobulin-like receptors (KIRs) which expressed by T and NK cells …

[HTML][HTML] NK cell adoptive immunotherapy of cancer: evaluating recognition strategies and overcoming limitations

CE Sanchez, EP Dowlati, AE Geiger… - … and cellular therapy, 2021 - Elsevier
Natural killer (NK) cells, the primary effector cells of the innate immune system, utilize
multiple strategies to recognize tumor cells by (1) detecting the presence of activating …

[HTML][HTML] Cancer resistance to immunotherapy: What is the role of cancer stem cells?

G Gupta, G Merhej, S Saravanan… - Cancer Drug Resistance, 2022 - ncbi.nlm.nih.gov
Immunotherapy is an emerging form of cancer therapy that is associated with promising
outcomes. However, most cancer patients either do not respond to immunotherapy or …

Chrysin and chrysin-loaded nanocarriers induced immunogenic cell death on B16 melanoma cells

Y Oliyapour, S Dabiri, O Molavi, MS Hejazi, S Davaran… - Medical Oncology, 2023 - Springer
Induction of immunogenic cell death (ICD) is a promising strategy for cancer
immunotherapy. Chrysin, which has potential anticancer effects, faces limitations in clinical …