Serum proteomics identifies S100A11 and MMP9 as novel biomarkers for predicting the early efficacy of sublingual immunotherapy in allergic rhinitis

Y Zhang, J Shui, L Wang, F Wang - International Immunopharmacology, 2023 - Elsevier
Background Allergic rhinitis (AR) is a chronic inflammatory disorder, and sublingual
immunotherapy (SLIT) is an important therapy. However, SLIT exhibits a wide range of …

Regulation of Macrophage Polarization in Allergy by Noncoding RNAs

O Ishibashi, SA Muljo, Z Islam - Non-coding RNA, 2023 - mdpi.com
Allergy is a type 2 immune reaction triggered by antigens known as allergens, including food
and environmental substances such as peanuts, plant pollen, fungal spores, and the feces …

Circulating exosomal has-miR-24-3p and has-miR-128-3p reflect early efficacy of sublingual immunotherapy in allergic rhinitis

S Cao, H Wu, Y Niu, L Wang, F Wang - International Immunopharmacology, 2023 - Elsevier
Objective Sublingual immunotherapy (SLIT) can improve the symptoms of allergic rhinitis
(AR) and modify its natural course, but its effectiveness varies among individuals. This study …

Serum exosome-derived miR-146a-3p promotes macrophage M2 polarization in allergic rhinitis by targeting VAV3 via PI3K/AKT/mTOR pathway

C Xia, K Zhu, Y Zhang, J Chen, C Yu, T Gao… - International …, 2023 - Elsevier
Background Our previous study showed that miR-146a-3p was elevated in serum exosomes
of allergic rhinitis (AR) patients, but the underlying mechanisms were unclarified. This study …

Intravital imaging of the human cornea reveals the differential effects of season on innate and adaptive immune cell morphodynamics

M Wu, X Zhang, S Karunaratne, J Lee, ER Lampugnani… - Ophthalmology, 2024 - Elsevier
Purpose While the external environment has been shown to shape the systemic human
immune landscape, defining the in vivo immune status of peripheral tissues has remained a …

Soluble TAM Receptor Tyrosine Kinases Correlate with Disease Severity and Predict the Early Responsiveness of Sublingual Immunotherapy in Allergic Rhinitis

Y Zhou, Z Feng, J Wen, C Yang… - Journal of Inflammation …, 2023 - Taylor & Francis
Background Allergic rhinitis (AR) is a common allergic disease, and SLIT has shown
effectiveness as a treatment method. This study focuses on the evaluation of serum TAM …

Aberrant expressions of TAM receptors are associated with postoperative recurrence in chronic rhinosinusitis with nasal polyps

Y Zhou, Z Feng, J Wen, C Yang, Q Jing - European Archives of Oto-Rhino …, 2024 - Springer
Abstract Objectives TAM receptors (TYRO3, AXL, and MER) play important roles in
inflammatory responses, but their effects in chronic rhinosinusitis with nasal polyps …

Clinical efficacy in one-year treatment with Artemisia annua-SLIT drops in monosensitized and polysensitized individuals

Z Shen, P Zhang, W Kang, X Chen, H Li, Y Shao… - American Journal of …, 2023 - Elsevier
Purpose Seasonal allergic rhinoconjunctivitis (SARC) caused by Artemisia seriously affects
patients' quality of life in northern China. This study aimed to estimate further the efficacy and …