Subarachnoid haemorrhage (SAH) is a form of stroke that is associated with substantial
morbidity, often as a result of cerebral ischaemia that occurs in the following days. These …

Acute stroke is associated with high morbidity and mortality. In the last decades, new
therapies have been investigated with the aim of improving clinical outcomes in the acute …

Object In spite of evidence that use of the Brain Trauma Foundation Guidelines for the
Management of Severe Traumatic Brain Injury (Guidelines) would dramatically reduce …

Subarachnoid hemorrhage (SAH) is a devastating stroke subtype with a high rate of
mortality and morbidity. The poor clinical outcome can be attributed to the biphasic course of …

Pressure autoregulation is an important hemodynamic mechanism that protects the brain
against inappropriate fluctuations in cerebral blood flow in the face of changing cerebral …

Background Guidelines recommend cerebral perfusion pressure (CPP) values of 50–70
mmHg and intracranial pressure lower than 20 mmHg for the management of acute …

Cerebral Autoregulation (CA) is an important physiological mechanism stabilizing cerebral
blood flow (CBF) in response to changes in cerebral perfusion pressure (CPP). By …

Traumatic brain injury (TBI) is a major health problem worldwide. In addition to its high
mortality (35–40%), survivors are left with cognitive, behavioral, and communicative …

Current neurointensive care guidelines recommend intracranial pressure (ICP) and cerebral
perfusion pressure (CPP) centered management for moderate-severe traumatic brain injury …

This comprehensive review summarizes the evidence regarding use of cerebral
autoregulation-directed therapy at the bedside and provides an evaluation of its impact on …