Green synthesis of polyphenol-grafted lignin nanoparticles and their application as sustainable anti-acne, antioxidant, and UV-blocking agents

WIY Abdelmula, BMT Gorish, S Sethupathy… - Colloids and Surfaces B …, 2025 - Elsevier
Acne is a persistent infectious skin condition primarily caused by Propionibacterium acne
that affects 80% of teenagers. The rise of antibiotic resistance in P. acnes has led to an …

Machine learning and molecular dynamics simulations predict potential TGR5 agonists for type 2 diabetes treatment

OA Enejoh, CH Okonkwo, H Nortey, OA Kemiki… - Frontiers in …, 2025 - frontiersin.org
Introduction Treatment of type 2 diabetes (T2D) remains a significant challenge because of
its multifactorial nature and complex metabolic pathways. There is growing interest in finding …

Study of the orphan GPR21 towards therapeutics for metabolic disorders

Σ Σκαρμαλιωράκη - 2024 - polynoe.lib.uniwa.gr
Since G-Protein Coupled Receptors (GPCRs) are engaged in a variety of signal
transduction pathways in many pathophysiological situations, they are important targets for …