A multi-epitope vaccine GILE against Echinococcus Multilocularis infection in mice

P Zhou, Z Zhou, M Huayu, L Wang, L Feng… - Frontiers in …, 2023 - frontiersin.org
Introduction The objective of this study is to construct a multi-epitope vaccine GILE
containing B-cell and T-cell epitopes against Echinococcus Multilocularis (E. multilocularis) …

Effect of Hydralazine on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Deficient Mice

Y Wang, O Sargisson, DT Nguyen, K Parker… - International Journal of …, 2023 - mdpi.com
The rupture of an abdominal aortic aneurysm (AAA) causes about 200,000 deaths
worldwide each year. However, there are currently no effective drug therapies to prevent …

Thermosensitive injectable hydrogels for intra-articular delivery of etanercept for the treatment of osteoarthritis

J García-Couce, T Schomann, CK Chung, I Que… - Gels, 2022 - mdpi.com
The intra-articular administration of drugs has attracted great interest in recent decades for
the treatment of osteoarthritis. The use of modified drugs has also attracted interest in recent …

Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E …

Y Wang, DT Nguyen, J Anesi, A Alramahi… - International Journal of …, 2023 - mdpi.com
This study aimed to investigate the effect of the sympatholytic drug moxonidine on
atherosclerosis. The effects of moxonidine on oxidised low-density lipoprotein (LDL) uptake …

[HTML][HTML] In vitro safety assessment of reduced graphene oxide in human monocytes and T cells.

Ó Cebadero-Dominguez, A Casas-Rodríguez… - Environmental …, 2023 - Elsevier
Considering the increase in the use of graphene derivatives in different fields, the
environmental and human exposure to these materials is likely, and the potential …

Synthesis, antiproliferative, antioxidant activities, in silico studies, DFT analysis and molecular dynamics simulation of novel 1-(4-chlorobenzhydryl) piperazine …

NA Al-Masoudi, RS Jihad, NA Abdul-Rida… - Journal of Molecular …, 2024 - Elsevier
Abstract A series of 1-(4-chlorobenzhydryl) piperazine derivatives 3–10 were synthesized
and characterized both spectroscopically and structurally to investigate their antiproliferative …

Discovery of highly oxygenated cytochalasans with antiproliferative activity from an endophytic fungus Boeremia exigua

C Tian, Y Feng, H Zhang, X Mao, X Zhu, X Wang… - Bioorganic …, 2025 - Elsevier
Abstract Eleven cytochalasans (1− 11), including six undescribed analogues (1− 3 and 5− 7)
and a new natural product (4), were obtained from the endophytic fungus Boeremia exigua …

Exploring the Diverse Biological Properties of Cannabidiol: A Focus on Plant Growth Stimulation

D Gruľová, B Baranová, R Francolino… - Chemistry & …, 2024 - Wiley Online Library
The aim of the current study was to compare some biological activities of edible oils
enriched with 10% of cannabidiol (CBD samples) from the Slovak market. In addition, hemp …

Equine muscle derived mesenchymal stem cells loaded with water-soluble curcumin: modulation of neutrophil activation and enhanced protection against intracellular …

T Franck, J Ceusters, H Graide, A Niesten… - International Journal of …, 2023 - mdpi.com
We investigated the antioxidant potential of equine mesenchymal stem cells derived from
muscle microbiopsies (mdMSCs), loaded by a water-soluble curcumin lysinate incorporated …

Design, Synthesis, Docking Studies and Molecular Dynamics Simulation of New 1, 3, 5‐Triazine Derivatives as Anticancer Agents Selectively Targeting Pancreatic …

S Asghar, S Hameed, NA Al‐Masoudi… - Chemistry & …, 2024 - Wiley Online Library
On the basis of remarkable anticancer profile of s‐triazine nucleus, a new series of 2‐
methoxy‐4‐(3‐morpholino‐5‐(arylamino) phenoxy) benzaldehyde derivatives 11 a–u was …