Leishmaniasis, a tropically neglected disease, is responsible for the high mortality and
morbidity ratio in poverty-stricken areas. Currently, no vaccine is available for the complete …

The incidence of neglected diseases in tropical countries, such as Leishmaniasis and
Chagas's disease, is attributed to a set of biological and ecological factors associated with …

The high potential of quinoline containing natural products and their derivatives in medicinal
chemistry led us to discover novel series of 25 compounds for the development of new …

Leishmaniasis is a neglected disease present in more than 88 countries. The currently
adopted chemotherapy faces challenges related to side effects and the development of …

Abstract Five coumarins (5, 7, 8-trimethoxycoumarin (1), sabandin (2), cubreuva lactone (3),
5, 7-dimethoxycoumarin (5) and braylin (6)), seven furoquinoline alkaloids (isopimpinelin …

Leishmaniasis is a neglected tropical disease caused by members of the Leishmania genus
of parasitic protozoa that cause different clinical manifestations of the disease. Current …

Human leishmaniasis is a neglected tropical disease which affects nearly 1.5 million people
every year, with Mexico being an important endemic region. One of the major defense …

Leishmaniasis is a group of neglected vector-borne tropical diseases caused by protozoan
parasites of the genus Leishmania that multiply within phagocytic cells and have a wide …

Conventional chemotherapy of cutaneous leishmaniasis (CL) is based on multiple
parenteral or intralesional injections with systemically toxic drugs. Aiming at a single-dose …

A leishmaniose é uma doença negligenciada que possui a grande maioria dos casos
registrados em países subdesenvolvidos e assim como outras doenças negligenciadas …