Pathophysiology of benign prostatic hyperplasia and benign prostatic enlargement: a mini-review

S Madersbacher, N Sampson, Z Culig - Gerontology, 2019 - karger.com
Benign prostatic hyperplasia (BPH), benign prostatic enlargement (BPE) and lower urinary
tract symptoms (LUTS) belong to the most frequent diseases in ageing men. Beyond the 6th …

Endocrine control of benign prostatic hyperplasia

S La Vignera, RA Condorelli, GI Russo, G Morgia… - …, 2016 - Wiley Online Library
Benign prostatic hyperplasia (BPH) is the most common benign proliferative disease among
aging men. Androgens play a key role in the development and growth of the male genital …

Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis

L Wang, K Li, X Lin, Z Yao, S Wang, X Xiong, Z Ning… - Cancer letters, 2019 - Elsevier
Evasion of apoptosis is a major contributing factor to the development of chemo-and
radiotherapy resistance. Therefore, activation of non-apoptotic programmed cell death …

The effect of metformin therapy on incidence and prognosis in prostate cancer: A systematic review and meta-analysis

K He, H Hu, S Ye, H Wang, R Cui, L Yi - Scientific reports, 2019 - nature.com
The relationship between metformin and prostate cancer (PCa) remains controversial. To
clarify this association, the PubMed, Embase and Cochrane library databases were …

Established and emerging treatments for diabetes-associated lower urinary tract dysfunction

BR Erdogan, G Liu, E Arioglu-Inan… - … Schmiedeberg's archives of …, 2022 - Springer
Dysfunction of the lower urinary tract (LUT) including urinary bladder and urethra (and
prostate in men) is one of the most frequent complications of diabetes and can manifest as …

[HTML][HTML] Metabolic syndrome and benign prostatic hyperplasia: an update

HY Ngai, KKS Yuen, CM Ng, CH Cheng… - Asian journal of urology, 2017 - Elsevier
Metabolic syndrome (MetS) is a cluster of metabolic abnormalities related to central
adiposity and insulin resistance. Its importance is increasingly recognized as it associates …

[HTML][HTML] The effect of metformin on male reproductive function and prostate: An updated review

CH Tseng - The World Journal of Men's Health, 2022 - ncbi.nlm.nih.gov
Metformin is the first-line oral antidiabetic drug that shows multiple pleiotropic effects of anti-
inflamation, anti-cancer, anti-aging, anti-microbia, anti-atherosclerosis, and immune …

Amelioration of testosterone-induced benign prostatic hyperplasia using febuxostat in rats: The role of VEGF/TGFβ and iNOS/COX-2

AM Abdel-Aziz, NFG El-Tahawy… - European Journal of …, 2020 - Elsevier
Benign prostatic hyperplasia (BPH) is a common male disorder. Febuxostat is a non-purine,
selective inhibitor of xanthine oxidase (XO), which has a strong antioxidant capacity and …

Chrysin attenuates testosterone-induced benign prostate hyperplasia in rats

SM Shoieb, A Esmat, AE Khalifa… - Food and Chemical …, 2018 - Elsevier
Benign prostate hyperplasia (BPH) is a common age-related health problem affecting almost
3 out of 4 men in their sixties. Chrysin is a dietary phytoestrogen found naturally in bee …

Icariin ameliorates metabolic syndrome-induced benign prostatic hyperplasia in rats

AA Aljehani, NA Albadr, MZ Nasrullah… - … Science and Pollution …, 2021 - Springer
Metabolic syndrome (MetS) is an immense health issue that causes serious complications in
aging males including BPH. Icariin (ICA) is a flavonol glycoside that exerts a plethora of …