Network news: the replication of kinetoplast DNA

RE Jensen, PT Englund - Annual review of microbiology, 2012 - annualreviews.org
One of the most fascinating and unusual features of trypanosomatids, parasites that cause
disease in many tropical countries, is their mitochondrial DNA. This genome, known as …

Fellowship of the rings: the replication of kinetoplast DNA

B Liu, Y Liu, SA Motyka, EEC Agbo, PT Englund - Trends in parasitology, 2005 - cell.com
Kinetoplastid protozoa such as trypanosomes and Leishmania are important because they
cause human disease. These parasites are named after one of their most unusual features …

The structure and replication of kinetoplast DNA

J Shlomai - Current molecular medicine, 2004 - ingentaconnect.com
Kinetoplast DNA (kDNA), the mitochondrial DNA of flagellated protozoa of the order
Kinetoplastida, is unique in its structure, function and mode of replication. It consists of few …

Mitochondrial genome maintenance—the kinetoplast story

S Amodeo, I Bregy, T Ochsenreiter - FEMS microbiology …, 2023 - academic.oup.com
Mitochondrial DNA replication is an essential process in most eukaryotes. Similar to the
diversity in mitochondrial genome size and organization in the different eukaryotic …

Comparison of the Mitochondrial Genomes and Steady State Transcriptomes of Two Strains of the Trypanosomatid Parasite, Leishmania tarentolae

L Simpson, SM Douglass, JA Lake… - PLoS neglected …, 2015 - journals.plos.org
U-insertion/deletion RNA editing is a post-transcriptional mitochondrial RNA modification
phenomenon required for viability of trypanosomatid parasites. Small guide RNAs encoded …

Replication of kinetoplast DNA: an update for the new millennium

JC Morris, ME Drew, MM Klingbeil, SA Motyka… - International journal for …, 2001 - Elsevier
In this review we will describe the replication of kinetoplast DNA, a subject that our lab has
studied for many years. Our knowledge of kinetoplast DNA replication has depended mostly …

Intramitochondrial localization of universal minicircle sequence-binding protein, a trypanosomatid protein that binds kinetoplast minicircle replication origins

K Abu-Elneel, DR Robinson, ME Drew… - The Journal of cell …, 2001 - rupress.org
Kinetoplast DNA (kDNA), the mitochondrial DNA of the trypanosomatid Crithidia fasciculata,
is a unique structure containing 5,000 DNA minicircles topologically linked into a massive …

Redox potential regulates binding of universal minicircle sequence binding protein at the kinetoplast DNA replication origin

I Onn, N Milman-Shtepel, J Shlomai - Eukaryotic cell, 2004 - Am Soc Microbiol
Kinetoplast DNA, the mitochondrial DNA of the trypanosomatid Crithidia fasciculata, is a
remarkable structure containing 5,000 topologically linked DNA minicircles. Their replication …

A Mitochondrial DNA Primase Is Essential for Cell Growth and Kinetoplast DNA Replication in Trypanosoma brucei

JC Hines, DS Ray - Molecular and cellular biology, 2010 - Taylor & Francis
Kinetoplast DNA in African trypanosomes contains a novel form of mitochondrial DNA
consisting of thousands of minicircles and dozens of maxicircles topologically interlocked to …

Universal minicircle sequence-binding protein, a sequence-specific DNA-binding protein that recognizes the two replication origins of the kinetoplast DNA minicircle

K Abu-Elneel, I Kapeller, J Shlomai - Journal of Biological Chemistry, 1999 - ASBMB
Replication of the kinetoplast DNA minicircle lagging (heavy (H))-strand initiates at, or near,
a unique hexameric sequence (5′-ACGCCC-3′) that is conserved in the minicircles of …