Every year, about 75 million units of blood are collected worldwide. Red blood cell (RBC)
transfusion is one of the few treatments that adequately restore tissue oxygenation when …

Background Acute blood loss in trauma requires quick identification and action to restore
circulating volume and save the patient. Massive transfusion protocols (MTPs) have become …

Objective: To determine the effect of blood component ratios in massive transfusion (MT), we
hypothesized that increased use of plasma and platelet to red blood cell (RBC) ratios would …

Background: Massive transfusion, the administration of 10 to more than 100 units of red
blood cells (RBC) in less than 24 hours, can be a life saving therapy in the treatment of …

Massive hemorrhage is associated with coagulopathy and high mortality. The transfusion
guidelines up to 2006 recommended that resuscitation of massive hemorrhage should occur …

Death due to trauma is the leading cause of lost life years worldwide, with haemorrhage
being responsible for 30-40% of trauma mortality and accounting for almost 50% of the …

Background: Several recent military and civilian trauma studies demonstrate that improved
outcomes are associated with early and increased use of plasma-based resuscitation …

Bleeding pelvic fractures that result in haemodynamic instability have a reported mortality
rate as high as 40%. Because of the extreme force needed to disrupt the pelvic ring …

RBCs distribute oxygen to tissues, but, paradoxically, blood transfusion does not always
improve oxygen delivery and is associated with ischemic events. We hypothesized that …

Background To test whether an acute transfusion practice of packed red blood cells (pRBC):
fresh‐frozen plasma (FFP) 1: 1 would be associated with reduced mortality in acute bleeding …