The current challenges in cancer treatment using conventional therapies have made the
emergence of nanotechnology with more advancements. The exponential growth of …

Despite the enormous potential of nanomedicines to shape the future of medicine, their
clinical translation remains suboptimal. Translational challenges are present in every step of …

Nanoparticles (NPs) are commonly functionalized using targeting ligands to drive their
selective uptake in cells of interest. Typical target cell types are cancer cells, which often …

Interactions of various ligands and receptors have been extensively investigated because
they regulate a series of signal transduction leading to various functional cellular outcomes …

RNA interference (RNAi) presents great potential against intractable liver diseases.
However, the establishment of specific, efficient, and safe delivery systems targeting …

The oral route is highly desirable for colorectal cancer (CRC) treatment because it allows
concentrating the drug in the colon and achieving a localized effect. However, orally …

Decorating nanoparticles with antibodies (Ab) is a key strategy for targeted drug delivery
and imaging. For this purpose, the orientation of the antibody on the nanoparticle is crucial …

Nanomaterials have revolutionized medicine by enabling control over drugs'
pharmacokinetics, biodistribution, and biocompatibility. However, most nanotherapeutic …

Nanoparticles (NPs) are commonly modified with tumor-targeting moieties that recognize
proteins overexpressed on the extracellular membrane to increase their specific interaction …

Nanoparticles (NPs) have proven their applicability in biosensing, drug delivery, and
photothermal therapy, but their performance depends critically on the distribution and …